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It is with deep sadness that we mourn the passing of Ulrich (Uli) Theopold, of Stockholm University, who passed away on September 23 after a long battle with cancer. We remember and honor his life and his work. Uli was a distinguished scholar, mentor, researcher, and a dedicated member of the editorial board of the Journal of Innate Immunity. He was a luminary in the world of innate immunity, leaving an indelible mark on the field and touching the lives of countless colleagues, students, and friends.