Publication

Durch Bromierung ausgelöste Umlagerung tertiärer Allylalkohole : Der Einfluß eines Fluor-Substituenten auf Reaktionsgeschwindigkeit und Reaktionsverlauf

Manfred Schlosser
1980
Journal Articles

Abstract

Reaction of Me3CCMe(OH)CR:CH2 (I; R = H) with Br2 or NBS in aq. medium resulted in rearrangement, yielding ketones Me3CCOCHMeCH2Br and MeCOCR(CH2Br)CMe3 (III) and the oxirane II. With I (R = F, Me), bromination gave only ketone III. Competition expts. showed that I (R = F) underwent bromination at a much slower rate than I (R = H or Me). [on SciFinder (R)]

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Manfred Schlosser
1980
Journal Articles

Abstract

Official source

Related concepts (16)

Reaction rate

The reaction rate or rate of reaction is the speed at which a chemical reaction takes place, defined as proportional to the increase in the concentration of a product per unit time and to the decrease in the concentration of a reactant per unit time. Reaction rates can vary dramatically. For example, the oxidative rusting of iron under Earth's atmosphere is a slow reaction that can take many years, but the combustion of cellulose in a fire is a reaction that takes place in fractions of a second.

Rearrangement reaction

In organic chemistry, a rearrangement reaction is a broad class of organic reactions where the carbon skeleton of a molecule is rearranged to give a structural isomer of the original molecule. Often a substituent moves from one atom to another atom in the same molecule, hence these reactions are usually intramolecular. In the example below, the substituent R moves from carbon atom 1 to carbon atom 2: Intermolecular rearrangements also take place.

Chemical reaction

A chemical reaction is a process that leads to the chemical transformation of one set of chemical substances to another. Classically, chemical reactions encompass changes that only involve the positions of electrons in the forming and breaking of chemical bonds between atoms, with no change to the nuclei (no change to the elements present), and can often be described by a chemical equation. Nuclear chemistry is a sub-discipline of chemistry that involves the chemical reactions of unstable and radioactive elements where both electronic and nuclear changes can occur.

Related publications (14)

Durch Bromierung ausgelöste Umlagerung tertiärer Allylalkohole : Der Einfluß eines Fluor-Substituenten auf Reaktionsgeschwindigkeit und Reaktionsverlauf

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