Publication
The production of four top quarks (tt(-)tt(-)) is studied with LHC proton-proton collision data samples collected by the CMS experiment at a center-of-mass energy of 13 TeV, and corresponding to integrated luminosities of up to 138 fb-1. Events that have no leptons (all-hadronic), one lepton, or two oppositesign leptons (where lepton refers only to prompt electrons or prompt muons) are considered. This is the first tt(-)tt(-) measurement that includes the all-hadronic final state. The observed significance of the tt(-)tt(-) signal in these final states of 3.9 standard deviations (1.5 expected) provides evidence for tt(-)tt(-) production, with a measured cross section of 36 +12 -11 fb. Combined with earlier CMS results in other final states, the signal significance is 4.0 standard deviations (3.2 expected). The combination returns an observed cross section of 17 ± 4 (stat) ± 3 (syst) fb, which is consistent with the standard model prediction.