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Development of next-generation microfluidic systems for enhanced, faster, and cost-effective immunoassays for tissue diagnostics - Ac electrothermal flow & Acoustofluidics

Muaz Salama Abdelmonem Draz

The application of microfluidics in the field of surface-based assays and more specifically, the spatial molecular profiling of tumor tissues has gained a lot of interest, especially with the increased interest in personalized medicine and targeted therapy ...

EPFL2023

Modeling and analysis of miniaturized magnetorheological valve for fluidic actuation

Sofia Lydia Ntella

Fluidic actuation enables movement in a wide range of mechanical systems, from simple laboratory devices to more complex industrial machinery. Fluids are used to generate motion of mechanical pieces. The term "fluids" encompasses two types of technologies: ...

EPFL2023

A Fast Hybrid Pressure-Correction Algorithm for Simulating Incompressible Flows by Projection Methods

Jiannong Fang

To enforce the conservation of mass principle, a pressure Poisson equation arises in the numerical solution of incompressible fluid flow using the pressure-based segregated algorithms such as projection methods. For unsteady flows, the pressure Poisson equ ...

2023

Dielectric Elastomer Actuator-Based Valveless Impedance-Driven Pumping for Meso- and Macroscale Applications

Yves Perriard, Yoan René Cyrille Civet, Thomas Guillaume Martinez, Armando Matthieu Walter, Amine Benouhiba, Francesco Clavica, Silje Ekroll Jahren

Impedance pumps are simple designs that allow the generation or amplification of flow. They are fluid-filled systems based on flexible tubing connected to tubing with different impedances. A periodic off-center compression of the flexible tubing causes the ...

2023

Influence of the shear stress on fine sediment exchanges with the substrate using UVP measurements

Giovanni De Cesare, Romain Maxime Dubuis

The dynamic of fine sediment in rivers is closely related to the interactions between fine particles, the riverbed and the flow conditions. The accumulation of fine sediment in the riverbed reduces vertical water exchanges and can have detrimental effects ...

2023

A Gyrokinetic Moment Model of the Plasma Boundary in Fusion Devices

Baptiste Jimmy Frei

The overall performance of fusion devices, such as tokamaks, is strongly correlated to the phenomena that occur in the boundary region, the outer plasma region that faces the wall of the device. The boundary plays a crucial role in regulating the heat and ...

EPFL2023

A comprehensive mathematical model for cardiac perfusion

Alfio Quarteroni, Francesco Regazzoni, Christian Vergara

The aim of this paper is to introduce a new mathematical model that simulates myocardial blood perfusion that accounts for multiscale and multiphysics features. Our model incorporates cardiac electrophysiology, active and passive mechanics, hemodynamics, v ...

Nature Portfolio2023

Mechanism balancing taxonomy

Simon Nessim Henein, Hubert Pierre-Marie Benoît Schneegans, Florent Cosandier

The balancing of mechanisms consists in distributing their moving masses, inertias, and elastic components in order to achieve key mechanical properties, such as the elimination of the shaking forces and moments exported onto their supporting structure or ...

2023

Strength and timing of primary and secondary vortices generated by a rotating plate

Karen Ann J Mulleners, Diego Francescangeli

Accurate predictions of how vortices grow, evolve, and separate from aerodynamic objects are desirable for various applications ranging from autonomous aerial vehicles to wind turbines. Here, we present an experimental characterisation of the formation pro ...

2023

Three-dimensional buoyant hydraulic fractures: finite volume release

Brice Tanguy Alphonse Lecampion, Andreas Möri

In impermeable media, a hydraulic fracture can continue to expand even without additional fluid injection if its volume exceeds the limiting volume of a hydrostatically loaded radial fracture. This limit depends on the mechanical properties of the surround ...

Cambridge University Press2023