Study of the impact of electrical heterogeneities in the right and left atrium on atrial fibrillation perpetuation

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Stabilized isogeometric discretizations on trimmed and union geometries, and weak imposition of the boundary conditions for the Darcy flow

Modern manufacturing engineering is based on a ``design-through-analysis'' workflow. According to this paradigm, a prototype is first designed with Computer-aided-design (CAD) software and then finalized by simulating its physical behavior, which usually i ...

EPFL2022

How Leibniz read Pascal’s Geometry: The Practice of Reading as Hybrid Hermeneutics in the Materiality of Leibniz’s Pascaliana

Simon François Dumas Primbault

Between 1675 and 1676, while in Paris, Gottfried Wilhelm Leibniz (1646–1716) got privileged access to some geometric manuscripts from late Blaise Pascal’s hand. Although said manuscripts are not extant, Leibniz’s reading notes were preserved, together with ...

2022

RADCAM-A radiation camera system combining foil bolometers, AXUV diodes, and filtered soft x-ray diodes

Basil Duval, Umar Sheikh, Luke Simons

Measurements of radiated power are critical for characterizing and optimizing tokamak performance. The RADCAM system, comprising arrays of foil bolometers, Absolute eXtreme UltraViolet (AXUV), and filtered soft x-ray diodes, has been constructed to provide ...

2022

ECG-Based Indices to Characterize Persistent Atrial Fibrillation Before and During Stepwise Catheter Ablation

Jean-Marc Vesin, Etienne Pruvot, Adrian Luca

Background: Consistently successful patient outcomes following catheter ablation (CA) for treatment of persistent atrial fibrillation (pers-AF) remain elusive. We propose an electrocardiogram (ECG) analysis designed to (1) refine selection of patients most ...

2021

Association of Heart Rate Variability With Silent Brain Infarcts in Patients With Atrial Fibrillation

Vincent Schlageter, Jean-Marc Vesin

Purpose: Silent brain infarcts (SBI) are frequently detected in patients with atrial fibrillation (AF), but it is unknown whether SBI are linked to autonomic dysfunction. We aimed to explore the association of autonomic dysfunction with SBI in AF patients. ...

FRONTIERS MEDIA SA2021

A Computational Study of the Electrophysiological Substrate in Patients Suffering From Atrial Fibrillation

Alfio Quarteroni, Andrea Manzoni

In the context of cardiac electrophysiology, we propose a novel computational approach to highlight and explain the long-debated mechanisms behind atrial fibrillation (AF) and to reliably numerically predict its induction and sustainment. A key role is pla ...

FRONTIERS MEDIA SA2021

Dynamics of Intraprocedural Dominant Frequency Identifies Ablation Outcome in Persistent Atrial Fibrillation

Jean-Marc Vesin, Andréa Buttu, Etienne Pruvot, Alain Pithon, Adrian Luca

Background: The role of dominant frequency (DF) in tracking the efficiency of a stepwise catheter ablation (step-CA) in persistent atrial fibrillation (peAF) remains poorly studied. We hypothesized that the DF time-course during step-CA displays divergent ...

2021

Generic vanishing in characteristic p > 0 and the geometry of theta divisors

Zsolt Patakfalvi

In this paper, we prove a strengthening of the generic vanishing result in characteristic p > 0 given in Hacon and Patakfalvi (Am J Math 138(4):963-998, 2016). As a consequence of this result, we show that irreducible Theta divisors are strongly F-regular ...

SPRINGER INTERNATIONAL PUBLISHING AG2022

Implantable Fiber Bragg Grating Sensor for Continuous Heart Activity Monitoring: Ex-Vivo and In-Vivo Validation

Silvestro Micera

Continuous and reliable cardiac function monitoring could improve medication adherence in patients at risk of heart failure. This work presents an innovative implantable Fiber Bragg Grating-based soft sensor designed to sense mechanical cardiac activity. T ...

IEEE-INST ELECTRICAL ELECTRONICS ENGINEERS INC2021

Homogenization-based design of microstructured membranes: wake flows past permeable shells

François Gallaire, Edouard Boujo, Pier Giuseppe Ledda, Giuseppe Antonio Zampogna

A formal framework to characterize and control/optimize the flow past permeable membranes by means of a homogenization approach is proposed and applied to the wake flow past a permeable cylindrical shell. From a macroscopic viewpoint, a Navier-like effecti ...

Cambridge University Press2021

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