Publication

Increasing the sensitivity of enzyme-based biosensors using copper-chloride and EDTA

Nico de Rooij
2012
Posters

Abstract

The effect of CuCl2 and EDTA on increasing the sensitivity of enzyme biosensors was evaluated. The experiments revealed that successive exposure of these solutions to our biosensors can increase the sensitivity of the glucose and lactate biosensors up to 88% and 50%, respectively.

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Nico de Rooij
2012
Posters

Abstract

Official source

Related concepts (18)

Biosensor

A biosensor is an analytical device, used for the detection of a chemical substance, that combines a biological component with a physicochemical detector. The sensitive biological element, e.g. tissue, microorganisms, organelles, cell receptors, enzymes, antibodies, nucleic acids, etc., is a biologically derived material or biomimetic component that interacts with, binds with, or recognizes the analyte under study. The biologically sensitive elements can also be created by biological engineering.

Glucose meter

A glucose meter, also referred to as a "glucometer", is a medical device for determining the approximate concentration of glucose in the blood. It can also be a strip of glucose paper dipped into a substance and measured to the glucose chart. It is a key element of glucose testing, including home blood glucose monitoring (HBGM) performed by people with diabetes mellitus or hypoglycemia. A small drop of blood, obtained from slightly piercing a fingertip with a lancet, is placed on a disposable test strip that the meter reads and uses to calculate the blood glucose level.

Glucose

Glucose is a sugar with the molecular formula . Glucose is overall the most abundant monosaccharide, a subcategory of carbohydrates. Glucose is mainly made by plants and most algae during photosynthesis from water and carbon dioxide, using energy from sunlight, where it is used to make cellulose in cell walls, the most abundant carbohydrate in the world. In energy metabolism, glucose is the most important source of energy in all organisms. Glucose for metabolism is stored as a polymer, in plants mainly as starch and amylopectin, and in animals as glycogen.

Related publications (1)

Increasing the sensitivity of enzyme-based biosensors using copper-chloride and EDTA

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Comprehensive in-situ Bioreactor Monitoring and Control Based on a Mid-Infrared Spectroscopic Sensor System