Contactless electrochemical actuator for microfluidic dosing

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The present disclosure provides a method and a microfluidic device for producing one or more combinatorial microcompartment comprising at least two sample species within a carrier phase, the microfluidic device comprising a target channel, a first sample s ...

Many natural materials are structured on different length scales. This structuring often leads to an intricate interplay between soft and stiff components, which significantly improves the fracture toughness of these materials. A class of soft material tha ...

Hydrodynamic cavitation is one of the major phase change phenomena and occurs with a sudden decrease in the local static pressure within a fluid. With the emergence of microelectromechanical systems (MEMS), high-speed microfluidic devices have attracted co ...

Thanks to recent advancements in synthetic biology, the dream of creating a synthetic cell has become feasible. However, due to its inherent complexity, one of the fundamental functions of all living systems, i.e., self-replication, remains to be introduce ...

Optical whispering-gallery-mode (WGM) microcavities offer great promise in ultrasensitive biosensors because of their unique ability to enable resonant recirculation of light to achieve strong light-matter interactions in microscale volumes. However, it re ...

This paper presents the computational fluid dynamics modeling of an additive manufacturing process that is candidate for the production of Gen IV nuclear reactor fuels. The modeled process combines the internal gelation to produce metal hydrous oxides with ...

The specific interaction between DNA and proteins constitutes one of the crucial elements in the regulation of gene expression. This thesis focuses on the development and optimization of two microfluidic-based technologies called SMiLE-seq and FloChIP that ...

My thesis advances the field of shape memory polymer (SMP) actuators by providing a versatile strategy to arbitrarily reconfigure large arrays of densely packed latching soft actuators. It exploits two key intrinsic characteristics of SMPs, which are their ...

This PhD thesis aims at developing a system which can measure the mechanical properties of fluidic samples in the picoliter range. The ultimate goal is the characterization of cancer cells and viscoelastic fluids (i.e. biological fluids), in order to study ...

Nuclear magnetic resonance (NMR), electron paramagnetic resonance (EPR) and ferromagnetic resonance (FMR) spectroscopy can open up the possibility of studying many scientifically and biologically relevant samples at the µm and sub-µm scale. Examples of vol ...

The interaction between the host and the pathogen is extremely complex and is affected by anatomical, physiological, and immunological diversity in the microenvironments, leading to phenotypic diversity of the pathogen. Phenotypic heterogeneity, defined as ...

Mammalian synthetic biology could be augmented through the development of high-throughput microfluidic systems that integrate cellular transfection, culturing, and imaging. We created a microfluidic chip that cultures cells and implements 280 independent t ...

The research described within this thesis is primarily motivated by two fields of science with reversed, yet complementary, approaches to addressing the same essential objective: manipulating and understanding the complex program of life. Whereas synthetic ...

Dielectric elastomer actuators (DEAs) are an attractive form of electromechanical transducer, possessing high energy densities, an efficient design, mechanical flexibility, high speed, and noiseless operation. They have been incorporated into a variety of ...

Essential in biomedical research is the necessity of gathering statistically relevant data about large populations of specific biological entities, e.g. organisms, cells or molecules, while preserving detailed information about each single entity under in ...

We report the continuous growth of spherical assemblies of silica and titania nanoparticles, which were pre-activated to produce hydroxyl/ peroxy groups on their surface, by flowing a colloid-in-dioctyl phthalate emulsion into a polydimethylsiloxane microf ...

We present a platform that combines microarrays and microfluidic techniques to measure four protein biomarkers in 1024 serum samples for a total of 4096 assays per device. Detection is based on a surface fluorescence sandwich immunoassay with a limit of de ...

Contamination of drinking water with arsenic is a recurring problem in both industrialized and developing countries. Supplies for large populations can have concentrations much higher than the permissible levels, set by the World Health Organization (WHO) ...

We describe the assembly of silica nanoparticles into superstructures with controlled shape and size. The individual nanoparticles are chemically linked to each other via silica bridges, thus providing high mechanical stability to the assembly. Key to cont ...

Contactless electrochemical actuator for microfluidic dosing

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Device and method for producing a combinatorial microcompartment within a carrier phase

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