Publications related to Local Shear Stress and Dyslipidemia Interfere with Actin Cyto-Skeleton and Lysosomal Organization Contributing to Vascular Fragility

Related publications (17)

Shear and steel-fibre reinforcement for the punching resistance of flat slabs at internal and edge columns

Reinforced concrete flat slabs consist of a continuous, thin concrete plate that rests on a grid of columns. The supporting surface of the columns is very small compared to the floor plan dimensions, leading to concentrations of shear forces near the colum ...

EPFL2024

Refractive Index Matched (RIM) PIV in Free Surface Flows of Particle-Laden Yield Stress Fluids

Christophe Ancey, Yanan Chen

Flow of lava, avalanches, mudslides, and many geophysical and planetary flow systems are examples of free-surface flows of Yield Stress Fluids (YSFs). This category of fluids is known for its dual behavior below- and above a yielding threshold for the appl ...

2024

Nanomechanical Modeling of the Bending Response of Silicon Nanowires

Yusuf Leblebici, Zuhal Tasdemir

Understanding the mechanical behavior of silicon nanowiresis essentialfor the implementation of advanced nanoscale devices. Although bendingtests are predominantly used for this purpose, their findings shouldbe properly interpreted through modeling. Variou ...

AMER CHEMICAL SOC2023

Homogenization theory captures macroscopic flow discontinuities across Janus membranes

Kevin Wittkowski, François Gallaire, Pier Giuseppe Ledda, Giuseppe Antonio Zampogna

Janus membranes, thin permeable structures with chemical and geometrical asymmetric properties, show great potential in industrial separation processes. Yet the link between the micro- and macro-scale behaviours of these membranes needs to be established r ...

Cambridge University Press2023

Investigation of the effect of mineral dissolution on the geomechanical behaviour of geomaterials

Taeheon Kim

Geotechnical engineering scenarios engaged in internal erosion or mineral dissolution were found worldwide, from CO2 sequestration projects to internal erosion of earth dams. Materials subjected to loss of solid phase from their internal fabric vary from s ...

EPFL2022

Multi-scale modeling of aggregate interlock phenomena in concrete

Mohit Pundir

In concrete structures, opened cracks contribute significantly to the transfer of shear and normal stresses through the contact forces occurring between fractured surfaces. Such contact forces are due to protruding asperities, engaged by interlocking and f ...

EPFL2021

Sirt6 deletion in bone marrow-derived cells increases atherosclerosis - Central role of macrophage scavenger receptor 1

Johan Auwerx

Aims: Sirtuin 6 (Sirt6) is a NAD(+)-dependent deacetylase that plays a key role in DNA repair, inflammation and lipid regulation. Sirt6-null mice show severe metabolic defects and accelerated aging. Macrophage-foam cell formation via scavenger receptors is ...

2020

Analysis of morphological and haemodynamical indexes in abdominal aortic aneurysms as preliminary indicators of intraluminal thrombus deposition

Alfio Quarteroni, Simone Deparis, Claudia Maria Colciago

In this paper we study the correlation between the Wall Shear Stress (WSS), a haemodynamical index derived from numerical simulations, and an new index MFA-ILT for the characterisation of intraluminal thrombus (ILT) in presence of abdominal aortic aneurysm ...

2020

Cyclic thermomechanical response of fine-grained soil-concrete interface for energy piles applications

Lyesse Laloui, Melis Sütman, Elena Ravera

Understanding the behaviour of soil-structure interfaces is critical for addressing the analysis and design of energy geostructures. In this study, the interface failure mechanism of energy piles (where a shear band is detached from the surrounding soil th ...

2020

Acute effects of transcatheter aortic valve replacement on the ventricular-aortic interaction

Nikolaos Stergiopoulos, Vasiliki Bikia, Georgios Rovas, Stamatia Zoi Pagoulatou

Transcatheter aortic valve replacement (TAVR) is increasingly used to treat severe aortic stenosis (AS) patients. However, little is known regarding the direct effect of TAVR on the ventricular-aortic interaction. In the present study, we aimed to investig ...

AMER PHYSIOLOGICAL SOC2020

Correction to: Numerical evaluation of test setups for determining the shear strength of masonry (vol 51, 110, 2018)

Katrin Beyer, Nicolas Richart, Shenghan Zhang

2019

Dislocation Cross-Slip in Face-Centered Cubic Solid Solution Alloys

Wolfram Georg Nöhring

The mechanical strength of metals depends on their resistance against various microscopic deformation processes. In ductile metals, the most important process is shearing of the crystal lattice by dislocations. One of the fundamental aspects of dislocation ...

EPFL2018

Screw dislocation structure and mobility in body centered cubic Fe predicted by a Gaussian Approximation Potential

Nicola Marzari, William Curtin, Francesco Maresca, Daniele Dragoni

The plastic flow behavior of bcc transition metals up to moderate temperatures is dominated by the thermally activated glide of screw dislocations, which in turn is determined by the atomic-scale screw dislocation core structure and the associated kink-pai ...

2018

An analysis of the shear-transfer actions in reinforced concrete members without transverse reinforcement based on refined experimental measurements

Aurelio Muttoni, Miguel Fernández Ruiz, Francesco Cavagnis

A traditional difficulty in the understanding of the role of the various shear transfer actions in members without transverse reinforcement has been a lack of detailed measurements on the development of shear cracking and their associated kinematics during ...

2018

Computational study of the risk of restenosis in coronary bypasses

Alfio Quarteroni, Christian Vergara

Coronary artery disease, caused by the buildup of atherosclerotic plaques in the coronary vessel wall, is one of the leading causes of death in the world. For high-risk patients, coronary artery bypass graft is the preferred treatment. Despite overall exce ...

Springer Heidelberg2017

Stress fields for the interaction of in-plane and out-of-plane forces in reinforced concrete shell elements

Marie-Rose Backes

Plane reinforced concrete (RC) elements are used in a large variety of structures. Their principal function is to carry forces that act in the plane of the element, but external actions and connections to other structural elements generally introduce addit ...

EPFL2017

Scaling description of non-local rheology

Matthieu Wyart

The plastic flow of amorphous materials displays non-local effects, characterized by a cooperativity length scale xi. We argue that these effects enter in the more general description of surface phenomena near critical points. Using this approach, we obtai ...

Royal Society of Chemistry2017