Publication

X-ray ablation of hyaluronan hydrogels: Fabrication of three-dimensional microchannel networks

Giorgio Margaritondo
2009
Journal Articles

Abstract

We present a simple and highly versatile protocol for polymer ablation: hard x-ray irradiation makes it possible to rapidly depolymerize hyaluronan hydrogels and fabricate three-dimensional network of microchannels. Photodynamic and photochemical analyses show that x-ray irradiation directly cleaves the polymer backbone and the total dose controls the degradation kinetics. This nonthermal ablation protocol may offer opportunities for processing organic polymers and biological materials.

Official source

https://infoscience.epfl.ch/entities/publication/33685cc1-a3f6-49a2-b9b1-339763ddf8b3

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X-ray ablation of hyaluronan hydrogels: Fabrication of three-dimensional microchannel networks

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