An optimized protocol for assessing changes in mouse whole-brain activity using opto-fMRI

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Amyotrophic lateral sclerosis (ALS) with only motor impairment (ALS-pure motor) and the behavioral variant of frontotemporal dementia (bvFTD) are hypothesized to represent extreme ends of a disease spectrum, which encompasses ALS with cognitive/behavioral ...

A key component in developing atrial digital twins (ADT) - virtual representations of patients’ atria — is the accurate prescription of myocardial fibers which are essential for the tissue characterization. Due to the difficulty of reconstructing atrial fi ...

Neural organoids and spheroids are three-dimensional (3D) in vitro brain models that mimic key aspects of human brain cellular composition, organization, and function. These models have become essential for studying brain development and neurological disor ...

For the EU DEMO conductor testing, a temperature sensor based on Fiber Bragg Grating (FBG) optical fiber is studied at the EPFL Swiss Plasma Center. The SULTAN test facility has been upgraded to use fiber optic sensor for temperature monitoring and quench ...

Subcortical brain structures such as the basal ganglia or the thalamus are involved in regulating motor and cognitive behavior. However, their contribution to perceptual consciousness is still unclear, due to the inherent difficulties of recording subcorti ...

Aim: Adolescents born very preterm (VPT;

Motivation is a multifaceted phenomenon that we explore within the framework of decision-making. Through this cognitive process, actions are directed towards specific goals by performing a trade-off between the cost and benefit of an action. The dorsomedia ...

The growing popularity of virtual reality systems has led to a renewed interest in understanding the neurophysiological correlates of the illusion of self-motion (vection), a phenomenon that can be both intentionally induced or avoided in such systems, dep ...

Obesity represents a significant public health concern and is linked to various comorbidities and cognitive impairments. Previous research indicates that elevated body mass index (BMI) is associated with structural changes in white matter (WM). However, a ...

To obtain an accurate cosmological inference from upcoming weak lensing surveys such as the one conducted by Euclid, the shear measurement requires calibration using galaxy image simulations. As it typically requires millions of simulated galaxy images and ...

The temporal variability of the thalamus in functional networks may provide valuable insights into the pathophysiology of schizophrenia. To address the complexity of the role of the thalamic nuclei in psychosis, we introduced micro-co-activation patterns ( ...

Recent decades have seen significant advancements in integrated photonics, driven by improvements in nanofabrication technology. This field has been developed from integrated semiconductor lasers and low-loss waveguides to optical modulators, enabling the ...

Animals, including humans, exhibit a remarkable variety of complex behaviours. How the nervous system controls all these behaviours ranging from simple, stereotyped movements to flexible, adaptive actions is a central questions of neuroscience. One of the ...

Humidity is a critical environmental factor in various applications, and its temperature dependence must be considered when developing thermo-hygrometer fiber sensors. The optical fibers that constitute the sensor must have a temperature reference, which s ...

CEBRA is a machine-learning method that can be used to compress time series in a way that reveals otherwise hidden structures in the variability of the data. It excels at processing behavioural and neural data recorded simultaneously, and it can decode act ...

Background: Sleep deprivation causes hippocampal injury, manifesting as neuronal damage and learning-memory impairment. These negative effects may be associated with disturbance of hippocampal glutamate and water homeostasis, which induces excessive neuron ...

Synaptic plasticity underlies the brain’s ability to learn and adapt. While experiments in brain slices have revealed mechanisms and protocols for the induction of plasticity between pairs of neurons, how these synaptic changes are coordinated in biologica ...

Previously, space-time wave packets (STWPs) have been gen-erated in free space with reduced diffraction and a tunable group velocity by combining multiple frequency comb lines each carrying a single Bessel mode with a unique wave num-ber. It might be poten ...

The motor learning process entails plastic changes in the brain, especially in brain network reconfigurations. In the current study, we sought to characterize motor learning by determining changes in the coupling behaviour between the brain functional and ...

Recordings of the physiological history of cells provide insights into biological processes, yet obtaining such recordings is a challenge. To address this, we introduce a method to record transient cellular events for later analysis. We designed proteins t ...

An optimized protocol for assessing changes in mouse whole-brain activity using opto-fMRI

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Longitudinal changes in MEG-based brain network topology of ALS patients with cognitive/behavioral impairment—An exploratory study

Defining myocardial fiber bundle architecture in atrial digital twins

Soft microelectrode arrays for 3D in vitro brain models

Quench Detection and Temperature Measurement With Fiber Optic Sensors

Subcortical correlates of consciousness with human single neuron recordings

Impact of a mindfulness-based intervention on neurobehavioral functioning and its association with large-scale brain networks in preterm young adolescents

Neurobiological and metabolic basis of motivation and effort-based decision-making - A human 1H-MRS, fMRI and machine learning study

Modulation of Visually Induced Self-motion Illusions by α Transcranial Electric Stimulation over the Superior Parietal Cortex

White adipose tissue distribution and amount are associated with increased white matter connectivity

Euclid: Improving the efficiency of weak lensing shear bias calibration

Thalamic contributions to psychosis susceptibility: Evidence from co-activation patterns accounting for intra-seed spatial variability (μCAPs)

Piezoelectric actuation for integrated photonics

Uncovering interactions between Descending Neurons as a functional principle of behavioural control

Humidity-insensitive optical fibers for distributed sensing applications

Brain dynamics uncovered using a machine-learning algorithm

Five percent CO2 inhalation alleviates hippocampal glutamate and water homeostasis disturbance, neuronal damage, and learning-memory impairment in sleep-deprived rats

Assemblies, synapse clustering and network topology interact with plasticity to explain structure-function relationships of the cortical connectome

Space-time wave packets with reduced divergence and tunable group velocity generated in free space after multi-mode fiber propagation

Brain connectome correlates of short-term motor learning in healthy older subjects

Recording physiological history of cells with chemical labeling