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The proton double quantum-carbon single quantum correlation experiment has been applied to designed peptides in the solid state in natural isotopic abundance. Analogous to nOe studies in solution, through-space double-quantum connectivities have been exploited to obtain the cis-trans conformational polymorphism of diproline residues occurring at beta-turns in the peptides.
Rizlan Bernier-Latmani, Marinella Mazzanti, Radmila Faizova, Ashley Richards Brown, Margaux Camille Andréa Molinas
Deyanira Graciela Cisneros Lazaro