Replicable effect of cortical-paired associative stimulation on response inhibition as a function of age

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Hemispheric asymmetry is a universal property of brain organization with wide implications into brain function and structure, and diseases. This study presents a laterality index for characterizing hemispheric asymmetries that underlie cortical maps using ...

Synaptic plasticity underlies the brain’s ability to learn and adapt. While experiments in brain slices have revealed mechanisms and protocols for the induction of plasticity between pairs of neurons, how these synaptic changes are coordinated in biologica ...

Spinal Cord Injury (SCI) affects almost 500,000 people every year, causing complete paralysis of both legs in severe cases, with no current treatment perspective. However, new neuroengineering technologies, such as the Brain Spine Interface (BSI), have eme ...

The relationship between age-related changes in brain structural connectivity (SC) and functional connectivity (FC) with cognition is not well understood. Furthermore, it is not clear whether cognition is represented via a similar spatial pattern of FC and ...

Essential tremor (ET) is the most common movement disorder. Its pathophysiology is only partially understood. Here, we leveraged graph theoretical analysis on structural covariance patterns quantified from morphometric estimates for cortical thickness, sur ...

Background: Age-related white matter lesions (WML) are common, impact neuronal connectivity, and affect motor function and cognition. In addition to pathological nigrostriatal losses, WML are also common co morbidities in Parkinson's disease (PD) that affe ...

Objective: To study motor cortex plasticity after a period of training with a new prototype of bidirectional hand prosthesis in three left trans-radial amputees, correlating these changes with the modification of Phantom Limb Pain (PLP) in the same period. ...

Stroke is one of the leading causes of long-term disability. Advanced technological solutions ("neurotechnologies'') exploiting robotic systems and electrodes that stimulate the nervous system can increase the efficacy of stroke rehabilitation. Recent stud ...

Previous single-site neurostimulation experiments have unsuccessfully attempted to shift decision-making away from habitual control, a fast, inflexible cognitive strategy, towards goal-directed control, a flexible, though computationally expensive strategy ...

The actionable space surrounding the body, referred to as peripersonal space (PPS), has been the subject of significant interest of late within the broader framework of embodied cognition. Neurophysiological and neuroimaging studies have shown the represen ...

Background Acute methanol poisoning leads to optic neuropathy and necrotic lesions of basal ganglia (BG) and subcortical white matter. Survivors of methanol poisoning exhibit long-term executive and memory deficits. Associations between brain volumetry par ...

Excitatory projection neurons of the neocortex are thought to play important roles in perceptual and cognitive functions of the brain by directly connecting diverse cortical and subcortical areas. However, many aspects of the anatomical and functional orga ...

The maturation of the cortical gray matter (GM) and white matter (WM) are described as sequential processes following multiple, but distinct rules. However, neither the mechanisms driving brain maturation processes, nor the relationship between GM and WM m ...

Electrophysiological and neuroimaging evidence suggest the existence of common mechanisms for monitoring erroneous events, independent of the source of errors. Previous works have described modulations of theta activity in the medial frontal cortex elicite ...

Studying body representations in the brain helps us to understand how we humans relate to our own bodies. The in vivo mapping of the somatosensory cortex, where these representations are found, is greatly facilitated by the high spatial resolution and high ...

Objectives To compare physiological noise contributions in cerebellar and cerebral regions of interest in high-resolution functional magnetic resonance imaging (fMRI) data acquired at 7T, to estimate the need for physiological noise removal in cerebellar f ...

An important feature of the nervous system is its ability to adapt to new stimuli. This adaptation allows for optimal encoding of the incoming information by dynamically changing the coding strategy based upon the incoming inputs to the neuron. At the leve ...

Primary sensory cortex discriminates incoming sensory information and generates multiple processing streams toward other cortical areas. However, the underlying cellular mechanisms remain unknown. Here, by making whole-cell recordings in primary somatosens ...

Whereas much is known about the degenerative effects of aging on cortical tissue, less is known about how aging affects visually evoked electrical activity, and at what latencies. We compared visual processing in elderly and young controls using a visual m ...

Replicable effect of cortical-paired associative stimulation on response inhibition as a function of age

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Multiscale Quantification of Hemispheric Asymmetry in Cortical Maps Using Geometric Eigenmodes

Assemblies, synapse clustering and network topology interact with plasticity to explain structure-function relationships of the cortical connectome

Brain-controlled spinal cord stimulation to restore mobility after spinal cord injury

Mapping of Structure-Function Age-Related Connectivity Changes on Cognition Using Multimodal MRI

Graph Theoretical Analysis of Structural Covariance Reveals the Relevance of Visuospatial and Attentional Areas in Essential Tremor Recovery After Stereotactic Radiosurgical Thalamotomy

Editorial: Fundamentals of 21st Century Neuroscience

Clinical correlates of white matter lesions in Parkinson's disease using automated multi-modal segmentation measures

Cortical plasticity after hand prostheses use: Is the hypothesis of deafferented cortex "invasion" always true?

Advanced Neurotechnologies for the Restoration of Motor Function

The effect of frontoparietal paired associative stimulation on decision-making and working memory

Increased Neural Strength and Reliability to Audiovisual Stimuli at the Boundary of Peripersonal Space

Methanol Poisoning as an Acute Toxicological Basal Ganglia Lesion Model: Evidence from Brain Volumetry and Cognition

Two-photon calcium imaging of neocortical projection neurons in whisker somatosensory cortex during goal-directed sensorimotor learning

Exploring the role of white matter connectivity in cortex maturation

Discriminant Brain Connectivity Patterns of Performance Monitoring at Average and Single-Trial Levels

Stroking or Buzzing? A Comparison of Somatosensory Touch Stimuli Using 7 Tesla fMRI

Physiological noise in human cerebellar fMRI

A new Mathematical Framework to Understand Single Neuron Computations

Membrane Potential Dynamics of Neocortical Projection Neurons Driving Target-Specific Signals

Age-related changes in visually evoked electrical brain activity