Publication

Engineering dendritic cell vaccines to improve cancer immunotherapy

Michele De Palma, Caleb Ricardo Perez
2019
Journal Articles

Abstract

At the interface between the innate and adaptive immune system, dendritic cells (DCs) play key roles in tumour immunity and hold a hitherto unrealized potential for cancer immunotherapy. Here we review the role of distinct DC subsets in the tumour microenvironment, with special emphasis on conventional type 1 DCs. Integrating new knowledge of DC biology and advancements in cell engineering, we provide a blueprint for the rational design of optimized DC vaccines for personalized cancer medicine.

Official source

https://infoscience.epfl.ch/entities/publication/31098787-f08c-4f39-99af-4e60caa3d952

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Engineering dendritic cell vaccines to improve cancer immunotherapy

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