Publication

Synchrotron spectromicroscopy of cobalt accumulation in granule cells, glial cells and GABAergic neurons

Giorgio Margaritondo
1996
Journal Articles

Abstract

Recent neurobiophysics experiments based on synchrotron spectromicroscopy indicated that aluminium is selectively accumulated by GABAergic neurons and glial cells rather than by granule cells. Does a similar cell specificity occur in the accumulation of other metals? We provide experimental evidence to the contrary: cobalt is found in granule cells at least with equal probability as in glial cells and GABAergic neurons. This result also confirms that neurobiophysics studies based on surface physics techniques have reached a stage of maturity.

Official source

https://infoscience.epfl.ch/entities/publication/2e3d107a-5e9b-4f14-9bce-123f56f3e5c6

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Giorgio Margaritondo
1996
Journal Articles

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/2e3d107a-5e9b-4f14-9bce-123f56f3e5c6

About this result

Related concepts (31)

Glia

Glia, also called glial cells (gliocytes) or neuroglia, are non-neuronal cells in the central nervous system (brain and spinal cord) and the peripheral nervous system that do not produce electrical impulses. The neuroglia make up more than one half the volume of neural tissue in our body. They maintain homeostasis, form myelin in the peripheral nervous system, and provide support and protection for neurons. In the central nervous system, glial cells include oligodendrocytes, astrocytes, ependymal cells and microglia, and in the peripheral nervous system they include Schwann cells and satellite cells.

Radial glial cell

Radial glial cells, or radial glial progenitor cells (RGPs), are bipolar-shaped progenitor cells that are responsible for producing all of the neurons in the cerebral cortex. RGPs also produce certain lineages of glia, including astrocytes and oligodendrocytes. Their cell bodies (somata) reside in the embryonic ventricular zone, which lies next to the developing ventricular system. During development, newborn neurons use radial glia as scaffolds, traveling along the radial glial fibers in order to reach their final destinations.

Probability space

In probability theory, a probability space or a probability triple is a mathematical construct that provides a formal model of a random process or "experiment". For example, one can define a probability space which models the throwing of a die. A probability space consists of three elements: A sample space, , which is the set of all possible outcomes. An event space, which is a set of events, , an event being a set of outcomes in the sample space. A probability function, , which assigns each event in the event space a probability, which is a number between 0 and 1.

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Synchrotron spectromicroscopy of cobalt accumulation in granule cells, glial cells and GABAergic neurons

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