Oxidative stressOxidative stress reflects an imbalance between the systemic manifestation of reactive oxygen species and a biological system's ability to readily detoxify the reactive intermediates or to repair the resulting damage. Disturbances in the normal redox state of cells can cause toxic effects through the production of peroxides and free radicals that damage all components of the cell, including proteins, lipids, and DNA. Oxidative stress from oxidative metabolism causes base damage, as well as strand breaks in DNA.
Nitrogen dioxideNitrogen dioxide is a chemical compound with the formula NO2. It is one of several nitrogen oxides. NO2 is an intermediate in the industrial synthesis of nitric acid, millions of tons of which are produced each year for use primarily in the production of fertilizers. At higher temperatures it is a reddish-brown gas. It can be fatal if inhaled in large quantities. Nitrogen dioxide is a paramagnetic, bent molecule with C2v point group symmetry. It is included in the NOx family of atmospheric pollutants.
Naturalism (philosophy)In philosophy, naturalism is the idea or belief that only natural laws and forces (as opposed to supernatural ones) operate in the universe. According to philosopher Steven Lockwood, naturalism can be separated into an ontological sense and a methodological sense. "Ontological" refers to ontology, the philosophical study of what exists. On an ontological level, philosophers often treat naturalism as equivalent to materialism. For example, philosopher Paul Kurtz argues that nature is best accounted for by reference to material principles.
Michael addition reactionIn organic chemistry, the Michael reaction or Michael 1,4 addition is a reaction between a Michael donor (an enolate or other nucleophile) and a Michael acceptor (usually an α,β-unsaturated carbonyl) to produce a Michael adduct by creating a carbon-carbon bond at the acceptor's β-carbon. It belongs to the larger class of conjugate additions and is widely used for the mild formation of carbon-carbon bonds.
PresentThe present is the period of time that is occurring now. The present is contrasted with the past, the period of time that has already occurred, and the future, the period of time that has yet to occur. It is sometimes represented as a hyperplane in space-time, typically called "now", although modern physics demonstrates that such a hyperplane cannot be defined uniquely for observers in relative motion. The present may also be viewed as a duration.
