Publications related to Natural Product Hybrids

Related publications (32)

Radical-Mediated Azidation of Benzylic C-H Bonds and Azidofunctionalization of Alkenes

Organic azides are known for their reactivity and broad applicability in organic synthesis. These compounds are pivotal in various chemical transformations, including nucleophilic substitution and cycloaddition reactions. Beyond synthetic chemistry, organi ...

EPFL2025

Harnessing modular approaches in the study of crystalline sorbents

Balázs Álmos Novotny

Sorbent are the workhorses of most contemporary separation processes. Crystalline sorbents boast descript structures that facilitate in silico study. Their diversity is matched by their varied applications. At the forefront of their currently researched ap ...

EPFL2025

Tension-tension fatigue behavior of basalt composite hybrid joints

Thomas Keller, Lulu Liu

The tension–tension fatigue behavior of pseudo-ductile hybrid bonded-bolted double lap basalt composite joints, composed of pseudo-ductile adhesives and adherends with multi-directional fiber architecture, was experimentally investigated. The fatigue damag ...

2024

Hybrid Simulator for Capturing Dynamics of Synthetic Populations

Michel Bierlaire, Marija Kukic

This paper presents a novel hybrid framework for generating and updating a synthetic population. We call it hybrid because it combines model-based and data-driven approaches. Existing generators produce a snapshot of synthetic data that becomes outdated ov ...

IEEE2024

Enhancing higher education through hybrid and flipped learning: Experiences from the GRE@T-PIONEeR project

Yi Zhang, Mathieu Hursin

GRE@T-PIONEeR is a Horizon 2020 project coordinated by Chalmers University of Technology, running over the period 2020-2024. 18 university teachers from 8 different universities located in 6 different countries gathered forces to develop and offer advanced ...

Elsevier Science Sa2024

Charge-Transfer States in Organic Nanowires

Lucile Annie Chassat

Charge separation processes in organic semiconductors play a pivotal role in diverse applications ranging from photovoltaics to photocatalysis. Understanding these mechanisms, particularly the role of hybrid charge-transfer (CT) states, is essential for ad ...

EPFL2024

Gyrokinetic simulations of turbulence in magnetic fusion plasmas using a delta-f PIC scheme with evolving background

Moahan Murugappan

Using the GKEngine code which simulates an electrostatic plasma with adiabatic electron response under a sheared-slab geometry, an attempt at developing a hybrid approach between the delta-f and full-f schemes to describe plasma profiles exhibiting high fl ...

EPFL2024

Structure-function analysis of the cyclic β-1,2-glucan synthase from Agrobacterium tumefaciens

Henning Paul-Julius Stahlberg, Dongchun Ni

The synthesis of complex sugars is a key aspect of microbial biology. Cyclic beta-1,2-glucan (C beta G) is a circular polysaccharide critical for host interactions of many bacteria, including major pathogens of humans (Brucella) and plants (Agrobacterium). ...

Nature Portfolio2024

A hybrid microscopic model for multimodal traffic with empirical observations from aerial footage

Nikolaos Geroliminis, Georgios Anagnostopoulos

Microscopic traffic flow models can be distinguished in lane-based or lane-free depending on the degree of lane-discipline. This distinction holds true only if motorcycles are neglected in lane-based traffic. In cities, as opposed to highways, this is an o ...

2023

Mechanopathology of biofilm-like Mycobacterium tuberculosis cords

Maria Gabriela Kirsch, Graham Knott, John McKinney, Neeraj Dhar, Nicolas Jean Philippe Guex, Mélanie Thérèse Marie Hannebelle, Vivek Vijay Thacker, Jessica Sordet, Kunal Sharma, Maxime Jan, Anaëlle Fabienne Dubois, Richa Mishra

Mycobacterium tuberculosis (Mtb) cultured axenically without detergent forms biofilm-like cords, a clinical identifier of virulence. In lung-on-chip (LoC) and mouse models, cords in alveolar cells contribute to suppression of innate immune signaling via nu ...

Cell Press2023

Playing Brains: The Ethical Challenges Posed by Silicon Sentience and Hybrid Intelligence in DishBrain

Georg Michael Joachim Starke

The convergence of human and artificial intelligence is currently receiving considerable scholarly attention. Much debate about the resulting Hybrid Minds focuses on the integration of artificial intelligence into the human brain through intelligent brain- ...

2023

Readiness evaluation of SOFC-MGT hybrid systems with carbon capture for distributed combined heat and power

Jan Van Herle, Jürg Alexander Schiffmann, Michele Gaffuri, Victoria Xu Hong He

The aggravation of climate change calls for the timely development and implementation of highly efficient, renewable, zero- or negative-emission energy solutions with high technological readiness and feasibility levels. Solid oxide fuel cells (SOFC) consti ...

Elsevier2023

Indoor Real-time localization system design for Internet of Things applications

Pooneh Mohaghegh

With the prevalence of smartphones, watches, and Internet of Things (IoT) devices, the ability to track their positions is becoming increasingly important. For many indoor positioning systems (IPSs), providing an uninterrupted flow of information in real-t ...

EPFL2023

New Methods for the Integrative Dynamic Modeling of Biomolecular Structures

Sylvain Träger

The true understanding of most cellular functions is only really achievable through the structural determination of their underlying macromolecular assemblies. However, their size, large number of individual components and metastable states make their eluc ...

EPFL2021

Nonlinear Frequency Conversion in the Hybrid Si3N4 - LiNbO3 Integrated Platform

Tobias Kippenberg, Junqiu Liu, Rui Ning Wang, Mikhail Churaev, Viacheslav Snigirev, Terence Albert Emile Blésin

We demonstrate optical frequency comb generation in hybrid high-Q optical microresonators fabricated using direct wafer bonding of photonic Damascene silicon nitride wafer with thin-film lithium niobate-on-insulator (LNOI). The devices enable direct phase ...

IEEE2021

Nonlinear Frequency Conversion in the Hybrid Silicon Nitride - Lithium Niobate Integrated Platform

Tobias Kippenberg, Junqiu Liu, Rui Ning Wang, Mikhail Churaev, Viacheslav Snigirev, Terence Albert Emile Blésin

We demonstrate optical frequency comb generation in hybrid high-Q optical microresonators fabricated using direct wafer bonding of photonic Damascene silicon nitride wafer with thin-film lithium niobate-on-insulator (LNOI). The devices enable direct phase ...

IEEE2021

Experimental and Numerical Study on Scour-Protection Methods in a Stilling Basin: Case Study of Chancy-Pougny Dam

Anton Schleiss, Giovanni De Cesare, Erik Bollaert, Sabine Chamoun, Davide Wüthrich

Chancy-Pougny is a run-of-river dam on the Swiss–French border constructed in the early 1920s. Since its commissioning, the operation of the four spillway gates has been responsible for a progressive erosion of the stilling basin. The future scour potentia ...

2021

Microresonator Dissipative Kerr Solitons Synchronized to an Optoelectronic Oscillator

Tobias Kippenberg, Wenle Weng, Jijun He

Using phase-modulation-induced potential gradient whose period is synchronized to a microwave opto-electronic oscillator, dissipative Kerr solitons generated in a crystalline optical microresonator are trapped by the soliton tweezing effect, exhibiting a s ...

American Physical Society (APS)2022

The high-power helicon program at DIII-D: gearing up for first experiments

Alessandro Marinoni

Helicon current drive (CD), also called fast wave CD in the lower hybrid range of frequencies, has long been regarded as a promising CD tool for reactor grade plasmas. A newly installed MW-level system at DIII-D will be the first test of this technology in ...

IOP Publishing Ltd2021

The PRK/Rubisco shunt strongly influences Arabidopsis seed metabolism and oil accumulation, affecting more than carbon recycling

Léo Arthur Bürgy

The carbon efficiency of storage lipid biosynthesis from imported sucrose in green Brassicaceae seeds is proposed to be enhanced by the PRK/Rubisco shunt, in which ribulose 1,5-bisphosphate carboxylase/oxygenase (Rubisco) acts outside the context of the Ca ...

2022