Publication

SYNTHESIS OF BIOLOGICAL ACTIVE UNDECAPEPTIDE SUBSTANCE-P WITH LIQUID-PHASE METHOD

1974
Journal Articles

Abstract

The synthesis of the biological active undecapeptide substance P with the liquid-phase method (LPM) is described. The over-all-yield of the synthesis is high and the peptide shows full biological activity. The synthesis demonstrates that the modification of the liquid-phase synthesis, the cristallisation method, enables the preparation of peptides in short time with high yield and purity.

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1974
Journal Articles

Abstract

Official source

Related concepts (14)

Liquid crystal

Liquid crystal (LC) is a state of matter whose properties are between those of conventional liquids and those of solid crystals. For example, a liquid crystal may flow like a liquid, but its molecules may be oriented in a crystal-like way. There are many types of LC phases, which can be distinguished by their optical properties (such as textures). The contrasting textures arise due to molecules within one area of material ("domain") being oriented in the same direction but different areas having different orientations.

Liquid–liquid extraction

Liquid–liquid extraction (LLE), also known as solvent extraction and partitioning, is a method to separate compounds or metal complexes, based on their relative solubilities in two different immiscible liquids, usually water (polar) and an organic solvent (non-polar). There is a net transfer of one or more species from one liquid into another liquid phase, generally from aqueous to organic. The transfer is driven by chemical potential, i.e.

Yield (chemistry)

In chemistry, yield, also referred to as reaction yield, is a measure of the quantity of moles of a product formed in relation to the reactant consumed, obtained in a chemical reaction, usually expressed as a percentage. Yield is one of the primary factors that scientists must consider in organic and inorganic chemical synthesis processes. In chemical reaction engineering, "yield", "conversion" and "selectivity" are terms used to describe ratios of how much of a reactant was consumed (conversion), how much desired product was formed (yield) in relation to the undesired product (selectivity), represented as X, Y, and S.

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