Publication

O-Fluoromethyl carboxylates and O-fluoromethyl carbamates

Manfred Schlosser
1995
Journal Articles

Abstract

The fluoride catalyzed reaction between acyl fluorides and monomeric formaldehyde affords fluoromethyl carboxylates in acceptable yields. Fluoromethyl fluoroformate, readily accessible from the corresponding dichloro compd., condenses with amines to give fluoromethyl carbamates. [on SciFinder (R)]

Official source

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Manfred Schlosser
1995
Journal Articles

Abstract

Official source

Related concepts (9)

Acyl halide

In organic chemistry, an acyl halide (also known as an acid halide) is a chemical compound derived from an oxoacid by replacing a hydroxyl group () with a halide group (, where X is a halogen). If the acid is a carboxylic acid (), the compound contains a functional group, which consists of a carbonyl group () singly bonded to a halogen atom. The general formula for such an acyl halide can be written RCOX, where R may be, for example, an alkyl group, CO is the carbonyl group, and X represents the halide, such as chloride.

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Sodium fluoride (NaF) is an inorganic compound with the formula . It is a colorless or white solid that is readily soluble in water. It is used in trace amounts in the fluoridation of drinking water to prevent tooth decay, and in toothpastes and topical pharmaceuticals for the same purpose. In 2020, it was the 265th most commonly prescribed medication in the United States, with more than 1 million prescriptions. It is also used in metallurgy and in medical imaging.