Biomimetic PEG hydrogels crosslinked with minimal plasmin-sensitive tri-amino acid peptides

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

Sensorineural hearing loss is a profound form of deafness, arising from damage to cochlear hair cells, which can be treated by limited clinical options such as cochlear implants. However, the implantation procedure carries the inherent risk of electrode in ...

This study examines the role of cavitation in drying cementitious materials. Classical nucleation theory is used to understand and study the parameters that influence cavitation pressures. The water desorption isotherms indicate that both heterogeneous and ...

This thesis investigates the water vapour sorption behaviour of samples with maximized calcium-silicate-hydrate (C-S-H) content. Primarily, the role of heterogeneous and homogeneous cavitation has been studied during the drying of cementitious materials. C ...

Alginic acid, a naturally occurring anionic polyelectrolyte, forms strong physically cross-linked hydrogels in the presence of metal cations. The latter engage in electrostatic interactions that compete with intra- and intermolecular hydrogen bonds, determ ...

Load-bearing tissues such as articular cartilage or meniscus are not infallible. They might fail due to trauma, over-solicitations, or diseases, which could subsequently alter the mobility of the patient. Repairing these damaged tissues in a minimally inva ...

Polymers containing PdnL2n complexes as network junctions were obtained by reaction of poly(ethylene glycol)-linked N-donor ligands with Pd2+. The addition of a metastable state photoacid renders the networks light sensitive, and gel–sol transitions can be ...

There has been a considerable interest in developing stiff, strong, tough, and highly stretchable hydrogels in various fields of science and technology including biomedical and sensing applications. However, simultaneous optimization of stiffness, strength ...

An alternative intracranial aneurysm embolic agent is emerging in the form of hydrogels due to their ability to be injected in liquid phase and solidify in situ. Hydrogels have the ability to fill an aneurysm sac more completely compared to solid implants ...

Gels made of telechelic polymers connected by reversible cross-linkers are a versatile design platform for biocompatible viscoelastic materials. Their linear response to a step strain displays a fast, near-exponential relaxation when using low-valence cros ...

The development of multifunctional encapsulation biomaterials could help the translation of cell‐based therapies into standard medical care. One of the major hurdles in the field of encapsulated cell transplantation is the current lack of materials present ...

Ought to their bioinert properties and facile synthesis, poly[(oligoethylene glycol)methacrylate]s (POEGMAs) have been raised as attractive alternatives to poly(ethylene glycols) (PEGs) in an array of (bio)material applications, especially when they are ap ...

Breast cancer is a significant global health burden, causing a substantial number of deaths. Systemic metastatic tumour cell dissemination is a major cause of poor outcomes. Understanding the mechanisms underlying metastasis is crucial for effective interv ...

Novel supramolecular gelators based on quinoline-indolin-2-one structure were synthesized. These gelators formed stable organogels in a mixture of DMSO/H2O (1:1). The scanning electron microscopy (SEM), IR and NMR spectroscopies, and rheological measuremen ...

Nature produces soft materials with fascinating combinations of mechanical properties. For example, the mussel byssus embodies a combination of stiffness and toughness, a feature that is unmatched by synthetic hydrogels. Key to enabling these excellent mec ...

The effect of increasing sulfate contents on the hydration of white cement was studied with a multi-technique approach. Quantitative X-Ray Diffraction (XRD) revealed that adding more gypsum in the cement resulted in more ettringite formation. Combining iso ...

The synthesis and control of properties of p-type ZnO is crucial for a variety of optoelectronic and spintronic applications; however, it remains challenging due to the control of intrinsic midgap (defect) states. In this study, we demonstrate a synthetic ...

Due to their selective crosslinking chemistry and well-defined mechano-biochemical characteristics, hydrogels crosslinked by thiol-Michael addition reactions have garnered immense interest for 3D cell culture applications. These hydrogels are typically for ...

The invention relates to a method for degradation of plastic materials into terephthalic acid (TPA)and/or ethylene glycol and/or other monomers that form the plastic materials. ...

By a micro-experimental methodology, we study the ongoing molecular process inside coarse fibrin networks by means of microrheology. We made these networks gelate around a probe microbead, allowing us to observe a temporal evolution compatible with the wel ...

This study aims to investigate the change with temperature of the water content of the C-(A)-S-H of plain cement (PC) and Limestone Calcined Clay Cement (LC3). The water content was determined by various methods: thermogravimetric analysis (TGA), H-1-nucle ...

Biomimetic PEG hydrogels crosslinked with minimal plasmin-sensitive tri-amino acid peptides

Chat with Graph Search

Additive manufacturing of flexible, biodegradable drug implants for sustained multi-drug release into the cochlea

The role of cavitation in drying cementitious materials

Characterization of water sorption cycle in the cement microstructure of controlled oxide composition

Competing Effects of Hydration and Cation Complexation in Single-Chain Alginate

Hybrid hydrogels for load-bearing implants

Light-induced assembly and disassembly of polymers with PdnL2n-type network junctions

Stiff, Strong, Tough, and Highly Stretchable Hydrogels Based on Dual Stimuli-Responsive Semicrystalline Poly(urethane–urea) Copolymers

Pulsatile Flow-Induced Fatigue-Resistant Photopolymerizable Hydrogels for the Treatment of Intracranial Aneurysms

Valence can control the nonexponential viscoelastic relaxation of multivalent reversible gels

Multicomponent Alginate-Derived Hydrogel Microspheres Presenting Hybrid Ionic-Covalent Network and Drug Eluting Properties

The Structural Dispersity of Oligoethylene Glycol-Containing Polymer Brushes Determines Their Interfacial Properties

Unveiling breast cancer metastasis through an advanced X-ray imaging approach

A smart low molecular weight gelator for the triple detection of copper (II), mercury (II), and cyanide ions in water resources

Localized Ionic Reinforcement of Double Network Granular Hydrogels

Effect of sulfate on C-S-H at early age

Tailoring p-Type Behavior in ZnO Quantum Dots through Enhanced Sol–Gel Synthesis: Mechanistic Insights into Zinc Vacancies

Low-Defect Thiol-Michael Addition Hydrogels as Matrigel Substitutes for Epithelial Organoid Derivation

Degradation of plastic materials into terephthalic acid (tpa), ethylene glycol and/or other monomers that form the plastic materials

Filamentous and step-like behavior of gelling coarse fibrin networks revealed by high-frequency microrheology

Effect of temperature on the water content of C-A-S-H in plain Portland and blended cements