Publication

Liquid encapsulated drug delivery device for acoustically-controlled release

2022

Abstract

Triggered release drug delivery is an innovative alternative to more intrusive ways of administrating a pharmaceutical compound. It allows precise location and timing of delivery with minimum harm to the patient. In the case of this project, the trigger is acoustic waves which activates the release of drug encapsulated into micro-devices that have previously been inserted into the patient's body. Those devices are a combination of a main body surrounding the drug and a sealing layer preventing the latter to spill (Figure 1). By a process explained later on, the acoustic waves' actuation will either separate the sealing layer from the main body or simply break it to release the drug at the desired location.

Official source

https://infoscience.epfl.ch/entities/publication/1d444a90-5713-4982-8352-b1642b9cfa41

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2022

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/1d444a90-5713-4982-8352-b1642b9cfa41

About this result

Related concepts (12)

Drug delivery

Drug delivery refers to approaches, formulations, manufacturing techniques, storage systems, and technologies involved in transporting a pharmaceutical compound to its target site to achieve a desired therapeutic effect. Principles related to drug preparation, route of administration, site-specific targeting, metabolism, and toxicity are used to optimize efficacy and safety, and to improve patient convenience and compliance. Drug delivery is aimed at altering a drug's pharmacokinetics and specificity by formulating it with different excipients, drug carriers, and medical devices.

Modified-release dosage

Modified-release dosage is a mechanism that (in contrast to immediate-release dosage) delivers a drug with a delay after its administration (delayed-release dosage) or for a prolonged period of time (extended-release [ER, XR, XL] dosage) or to a specific target in the body (targeted-release dosage). Sustained-release dosage forms are dosage forms designed to release (liberate) a drug at a predetermined rate in order to maintain a constant drug concentration for a specific period of time with minimum side effects.

Drug

A drug is any chemical substance that causes a change in an organism's physiology or psychology when consumed. Drugs are typically distinguished from food and substances that provide nutritional support. Consumption of drugs can be via inhalation, injection, smoking, ingestion, absorption via a patch on the skin, suppository, or dissolution under the tongue. In pharmacology, a drug is a chemical substance, typically of known structure, which, when administered to a living organism, produces a biological effect.