Simulation-based evaluation of susceptibility distortion correction methods in diffusion MRI for connectivity analysis

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On the cortical connectivity in the macaque brain: A comparison of diffusion tractography and histological tracing data

Jean-Philippe Thiran, Giorgio Innocenti, Gabriel Girard, Maxime Descoteaux, Tim Bjørn Dyrby

Diffusion-weighted magnetic resonance imaging (DW-MRI) tractography is a non-invasive tool to probe neural connections and the structure of the white matter. It has been applied successfully in studies of neurological disorders and normal connectivity. Rec ...

2020

DWI Simulation-Assisted Machine Learning Models for Microstructure Estimation

Jean-Philippe Thiran, Muhamed Barakovic, Gabriel Girard, Jonathan Rafael Patino Lopez, Erick Jorge Canales Rodriguez, Marco Pizzolato, Thomas Yu

Diffusion MRI (DW-MRI) allows for the detailed exploration of the brain white matter microstructure, with applications in both research and the clinic. However, state-of-the-art methods for microstructure estimation suffer from known limitations, such as t ...

Springer Nature2020

Dynamic spatiotemporal patterns of brain connectivity reorganize across development

Patric Hagmann, Marie Schaer, Alessandra Griffa, Emeline Mullier

Late human development is characterized by the maturation of high-level functional processes, which rely on reshaping of white matter connections, as well as synaptic density. However, the relationship between the whole-brain dynamics and the underlying wh ...

MIT PRESS2020

Apparent diffusion coefficient measured by diffusion MRI of moving and deforming domains

Jan Sickmann Hesthaven

The modeling of the diffusion MRI signal from moving and deforming organs such as the heart is challenging due to significant motion and deformation of the imaged medium during the signal acquisition. Recently, a mathematical formulation of the Bloch-Torre ...

Academic Press Inc - Elsevier Science2020

Human Cochlear Nucleus on 7 Tesla Diffusion Tensor Imaging: Insights Into Micro-anatomy and Function for Auditory Brainstem Implant Surgery

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Objective:The cochlear nucleus (CN) is the target of the auditory brainstem implant (ABI). Most ABI candidates have Neurofibromatosis Type 2 (NF2) and distorted brainstem anatomy from bilateral vestibular schwannomas. The CN is difficult to characterize as ...

LIPPINCOTT WILLIAMS & WILKINS2020

Exploring dynamic functional connectivity by incorporating prior knowledge of brain structure

Anjali Bagunu Tarun

The synchronized firing of distant neuronal populations gives rise to a wide array of functional brain networks that underlie human brain function. Given the enormous perception, learning, and cognition potential of the human brain, it is not surprising th ...

EPFL2020

Multiple sclerosis cortical and WM lesion segmentation at 3T MRI: a deep learning method based on FLAIR and MP2RAGE

Jean-Philippe Thiran, Meritxell Bach Cuadra, Ahmed Abdulkadir, Cristina Granziera, Mario Joao Fartaria de Oliveira, Po-Jui Lu, Muhamed Barakovic, Francesco La Rosa

The presence of cortical lesions in multiple sclerosis patients has emerged as an important biomarker of the disease. They appear in the earliest stages of the illness and have been shown to correlate with the severity of clinical symptoms. However, cortic ...

2020

Adaptive phase correction of diffusion-weighted images

Jean-Philippe Thiran, Maxime Descoteaux, Marco Pizzolato

Phase correction (PC) is a preprocessing technique that exploits the phase of images acquired in Magnetic Resonance Imaging (MRI) to obtain real-valued images containing tissue contrast with additive Gaussian noise, as opposed to magnitude images which fol ...

2020

Towards quantitative brain connectomics: microstructure informed tractography via convex optimization

Muhamed Barakovic

Tractography is the only non-invasive technique which is used to reconstruct the white mat- ter structural connectivity of the human brain. It relies on a specific Magnetic Resonance Imaging (MRI) acquisition, called diffusion MRI, which is sensitive to th ...

EPFL2019

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