Chlorination of arenes via the degradation of toxic chlorophenols

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A new procedure for the synthesis of highly substituted 1,3-diaminopyrazoles is described. As substrates, we have employed 1-alkynyltriazenes and imines. The formation of pyrazoles was achieved by two-fold C–N coupling reactions in the presence of (JohnPho ...

The susceptibility of waterborne viruses to different inactivating treatments is acknowledged to vary between viruses and even between closely related strains, yet the extent of this variation, or the underlying mechanisms, are not known. Here, different e ...

Waterborne viruses can exhibit resistance to common water disinfectants, yet the mechanisms that allow them to tolerate disinfection are poorly understood. Here, we generated echovirus 11 (E11) with resistance to chlorine dioxide (ClO2) by experimental evo ...

Common water disinfectants like chlorine have been reported to select for resistant viruses, yet little attention has been devoted to characterizing disinfection resistance. Here, we investigated the resistance of MS2 coliphage to inactivation by chlorine ...

Chlorine dioxide (ClO2) is commonly used as an alternative disinfectant to chlorine in drinking water treatment because it produces limited concentrations of halogenated organic disinfection byproducts. During drinking water treatment, the primary ClO2 byp ...

(Hetero)Aryl amines, an important class of organic molecules in medicinal chemistry, are most commonly synthesized from anilines, which are in turn synthesized by hydrogenation of nitroarenes. Amine synthesis directly from nitroarenes is attractive due to ...

The susceptibility of waterborne viruses to disinfection is known to vary between viruses and even between closely related strains, yet the extent of this variation is not known. Here, different enteroviruses (six strains of coxsackievirus B5, two strains ...

Disinfection processes such as chlorination, chloramination, and ozonation are a crucial measure to provide safe drinking water because they effectively inactivate pathogenic microorganisms. However, these processes can also lead to the formation of harmfu ...

Reported herein is an unprecedented copper-catalyzed arylation of remote C(sp3)-H bonds. Stirring a trifluorotoluene solution of either N fluorocarboxamides or N-fluorosulfonamides and arylboronic acids in the presence of a catalytic amount of copper(II) t ...

The first examples of Cu-catalyzed gamma-selective allylic alkenylation using organozinc reagents are reported. (E)-Alkenylzinc iodides were prepared by Fe-catalyzed reductive coupling of terminal arylalkynes with alkyl iodides. In the presence of a copper ...

Chlorination of arenes via the degradation of toxic chlorophenols

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Gold-Catalyzed Synthesis of 1,3-Diaminopyrazoles from 1-Alkynyltriazenes and Imines

Susceptibility of Enterovirus B strains to disinfectants and heat

Resistance of echovirus 11 to ClO2 is associated with enhanced host receptor use, altered entry routes and high fitness

Genetic, structural and phenotypic properties of MS2 coliphage with resistance to ClO2 disinfection

In Situ Formation of Free Chlorine During ClO2 Treatment: Implications on the Formation of Disinfection Byproducts

Amine synthesis via iron-catalysed reductive coupling of nitroarenes with alkyl halides

Variability in Disinfection Resistance between Currently Circulating Enterovirus B Serotypes and Strains

Formation of N-nitrosodimethylamine during water disinfection with chloramine : insights into reaction mechanisms from isotope fractionation analyses

Copper-Catalyzed Arylation of Remote C(sp3 )−H Bonds in Carboxamides and Sulfonamides

gamma-Selective Allylation of (E)-Alkenylzinc Iodides Prepared by Reductive Coupling of Arylacetylenes with Alkyl Iodides