Publications related to Recent Progress in Polymorphism-Based Population Genetic Inference

Related publications (36)

A positivity robust strategy to study effects of switching treatment

In studies of medical treatments, individuals often experience post-treatment events that predict their future outcomes. In this work, we study how to use initial observations of a recurrent event - a type of post-treatment event - to offer updated treatme ...

2025

Simulation-based Microstructure Imaging: Towards Realistic White Matter Modeling using Monte Carlo Methods in DW-MRI

Juan Luis Villarreal Haro

Over the last two decades, Diffusion-Weighted Magnetic Resonance Imaging (DW-MRI) has been developed as a powerful MR imaging modality that allows estimating non-invasively the microscopic structure of biological tissues by exploiting the natural motion of ...

EPFL2025

PolyCLEAN: Atomic optimization for super-resolution imaging and uncertainty estimation in radio interferometry

Julien René Fageot, Matthieu Martin Jean-André Simeoni, Sepand Kashani, Adrian Thibault Etienne Jarret, Joan Rue Queralt

Context. Imaging in radio interferometry requires solving an ill-posed noisy inverse problem, for which the most adopted algorithm is the original CLEAN algorithm and its variants. Alternative explicit optimization methods have gained increasing attention, ...

EDP SCIENCES S A2025

Statistical Inference for Inverse Problems: From Sparsity-Based Methods to Neural Networks

Pakshal Narendra Bohra

In inverse problems, the task is to reconstruct an unknown signal from its possibly noise-corrupted measurements. Penalized-likelihood-based estimation and Bayesian estimation are two powerful statistical paradigms for the resolution of such problems. They ...

EPFL2024

Estimation and control under uncertainty with application to power systems

Jean-Sébastien Hubert Brouillon

The transition to sustainable energy demands a fundamental redesign of the electrical grid, especially at the distribution level. With the increasing deployment of distributed energy resources, the development of reliable models, accurate state estimation ...

EPFL2024

Lower Bounds on the Bayesian Risk via Information Measures

Michael Christoph Gastpar, Amedeo Roberto Esposito, Adrien Vandenbroucque

This paper focuses on parameter estimation and introduces a new method for lower bounding the Bayesian risk. The method allows for the use of virtually any information measure, including Rényi's α, φ-divergences, and Sibson's α-Mutual Information. The appr ...

2024

Spectral Estimators for High-Dimensional Matrix Inference

Farzad Pourkamali

A key challenge across many disciplines is to extract meaningful information from data which is often obscured by noise. These datasets are typically represented as large matrices. Given the current trend of ever-increasing data volumes, with datasets grow ...

EPFL2024

Random matrix methods for high-dimensional machine learning models

Antoine Philippe Michel Bodin

In the rapidly evolving landscape of machine learning research, neural networks stand out with their ever-expanding number of parameters and reliance on increasingly large datasets. The financial cost and computational resources required for the training p ...

EPFL2024

Graph generative deep learning models with an application to circuit topologies

Igor Krawczuk

Modern integrated circuits are tiny yet incredibly complex technological artifacts, composed of millions and billions of individual structures working in unison. Managing their complexity and facilitating their design drove part of the co-evolution of mode ...

EPFL2024

Waterborne Virus Transport and Risk Assessment in Lake Geneva Under Climate Change

Tamar Kohn, Chaojie Li

Climate changes influence lake hydrodynamics and radiation levels and thus may affect the fate and transport of waterborne pathogens in lakes. This study examines the impact of climate change on the fate, transport, and associated risks of four waterborne ...

2024

Reproductive isolation arises during laboratory adaptation to a novel hot environment

Ana Marija Jaksic

Background: Reproductive isolation can result from adaptive processes (e.g., ecological speciation and mutation-order speciation) or stochastic processes such as "system drift" model. Ecological speciation predicts barriers to gene flow between populations ...

BMC2024

Algorithm 1044: PyGenStability, a Multiscale Community Detection with Generalized Markov Stability

Adám Gosztolai

We present PyGenStability, a general-use Python software package that provides a suite of analysis and visualization tools for unsupervised multiscale community detection in graphs. PyGenStability finds optimized partitions of a graph at different levels o ...

2024

OASIS: An integrated optimisation framework for activity scheduling

Janody Pougala

Activity-based models offer the potential for a far deeper understanding of daily mobility behaviour than trip-based models. Based on the fundamental assumption that travel demand is derived from the need to do activities, they are flexible tools that aim ...

EPFL2024

Optimal regimes for algorithm-assisted human decision-making

Mats Julius Stensrud, Aaron Leor Sarvet, Julien David Laurendeau

We consider optimal regimes for algorithm-assisted human decision-making. Such regimes are decision functions of measured pre-treatment variables and, by leveraging natural treatment values, enjoy a superoptimality property whereby they are guaranteed to o ...

2024

Deciphering the nature of cell state transitions in single cells using quantitative modeling of temporal dynamics

Alex Russell Lederer

Cells are the smallest operational units of living systems. Through synthesis of various biomolecules and exchange of signals with the environment, cells tightly regulate their composition to realize a specific functional state. The transformation of a cel ...

EPFL2024

How Stress Barriers and Fracture Toughness Heterogeneities Arrest Buoyant Hydraulic Fractures

Brice Tanguy Alphonse Lecampion, Carlo Peruzzo, Andreas Möri

In our study, we investigated the impact of changes in Mode I fracture toughness and stress barriers on fully developed planar, buoyant hydraulic fractures assuming linear elastic hydraulic fracture mechanics. We present scaling-based arguments to predict ...

Springer Wien2024

Boosting likelihood learning with event reweighting

Andrea Wulzer, Alfredo Glioti, Siyu Chen

Extracting maximal information from experimental data requires access to the likelihood function, which however is never directly available for complex experiments like those performed at high energy colliders. Theoretical predictions are obtained in this ...

Springer Nature2024

Impact of population size on early adaptation in rugged fitness landscapes

Anne-Florence Raphaëlle Bitbol, Richard Marie Servajean

Owing to stochastic fluctuations arising from finite population size, known as genetic drift, the ability of a population to explore a rugged fitness landscape depends on its size. In the weak mutation regime, while the mean steady-state fitness increases ...

ROYAL SOC2023

Analysing the potential for modal shiftbased on the logic of modal choice

Vincent Kaufmann, Ludy Juliana González Villamizar, Eloi Antoine Maël Bernier, Florian Lucien Jacques Masse

This article explores how the logic underlying modal practices tends to modulate the population’s responsiveness to improvements in global transport supply. Based on a quantitative survey conducted in 2018–2019 among the working population of the cantons o ...

2023

Higher Order Asymptotics: Applications to Satellite Conjunction and Boundary Problems

Soumaya Elkantassi

Higher-order asymptotics provide accurate approximations for use in parametric statistical modelling. In this thesis, we investigate using higher-order approximations in two-specific settings, with a particular emphasis on the tangent exponential model. ...

EPFL2023