Synthesis and direct assay of large macrocycle diversities by combinatorial late-stage modification at picomole scale

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The present invention relates to a method for analyzing cellular responsiveness to hormones or drags in a tissue sample based on an alginate-based 3D ex vivo culture system for normal and malignant tissue microstructures and uses thereof. ...

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Synthesis and direct assay of large macrocycle diversities by combinatorial late-stage modification at picomole scale

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