Portable bioluminescence systems and methods for in vivo monitoring of molecular and metabolic events in animals

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[Fe]-hydrogenase hosts an iron-guanylylpyridinol (FeGP) cofactor. The FeGP cofactor contains a pyridinol ring substituted with GMP, two methyl groups, and an acylmethyl group. HcgC, an enzyme involved in FeGP biosynthesis, catalyzes methyl transfer from S- ...

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The stereospecific oxidative decomposition of urate into allantoin is the core of purine catabolism in many organisms. The spontaneous decomposition of upstream intermediates and the nonenzymatic racemization of allantoin lead to an accumulation of (R)-all ...

[Fe]-hydrogenase is a newly characterized type of hydrogenase. This enzyme heterolytically splits hydrogen in the presence of a natural substrate. The active site of the enzyme contains a mono-iron complex with intriguing ironacyl ligation. Several groups ...

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The preparation of oligoribonucleotides is of great interest for structural and functional investigations in biomolecular chemistry and biology. Relevant RNAs are relatively long and contain often modifications. Two methods for their preparation are curren ...

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Institut fur Pflanzengenetik und Kulturpflanzenforschung (IPK), Corrensstr. 3, D-06466 Gatersleben, Germany. A complex mixture of fatty acid-derived aldehydes, ketones, and alcohols is released upon wounding of the moss Physcomitrella patens. To investigat ...

Portable bioluminescence systems and methods for in vivo monitoring of molecular and metabolic events in animals

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Probiotics and gut microbiome-Prospects and challenges in remediating heavy metal toxicity

Modeling, predicting and mining metabolism at atom-level resolution

Algorithms and flowchart for the design of synthetic biochemical networks

A novel cell-based sensor detecting the activity of individual basic proprotein convertases

Enzymes for second generation biofuels: recent developments and future perspectives

A Water-Bridged H-Bonding Network Contributes to the Catalysis of the SAM-Dependent C-Methyltransferase HcgC

Alkaline phosphatase-fused repebody as a new format of immuno-reagent for an immunoassay

iSCHRUNK – In Silico Approach to Characterization and Reduction of Uncertainty in the Kinetic Models of Genome-scale Metabolic Networks

NRK1 controls nicotinamide mononucleotide and nicotinamide riboside metabolism in mammalian cells

Reaction Mechanism and Catalytic Fingerprint of Allantoin Racemase

[Fe]-hydrogenase and Models Containing An Iron-Acyl Ligation

The DprE1 enzyme, one of the most vulnerable targets of Mycobacterium tuberculosis

Functional Genotyping of Sulfurospirillum spp. in Mixed Cultures Allowed the Identification of a New Tetrachloroethene Reductive Dehalogenase

Structure and function of the transketolase from Mycobacterium tuberculosis and comparison with the human enzyme

A Novel Yeast-Based Platform for Small Molecule Target Deconvolution Reveals Previously Unknown Binding Partners for the Approved Drugs Erlotinib, Atorvastatin, and Sulfasalazine

Optimized methods for the enzymatic ligation of oligoribonucleotides and analogues

Integrated nanoreactor system : triggering (bio-)chemical reactions in single vesicles

The Laboratory in a Droplet

A Multifunctional Lipoxygenase with Fatty Acid Hydroperoxide Cleaving Activity from the Moss Physcomitrella patens