Publication

Dispositif et procédé pour l'évaluation de la contraction cellulaire

Boris Hinz, Pierre Jean Arnould Wipff
2017
Patents

Abstract

A method for assessing cell contraction includes adhering contractile cells to an oxidized and cellular adhesion activated surface of a biocompatible silicone elastomer film. The biocompatible silicone elastomer film allows the cells to contract and wrinkles when the cells contract. Wrinkles in the biocompatible silicone elastomer film formed by contraction of the contractile cells are analyzed to assess cell contraction.

Official source

https://infoscience.epfl.ch/entities/publication/14871399-6677-432e-85d9-06b2e981e393

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Boris Hinz, Pierre Jean Arnould Wipff
2017
Patents

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/14871399-6677-432e-85d9-06b2e981e393

About this result

Related concepts (9)

Cell adhesion

Cell adhesion is the process by which cells interact and attach to neighbouring cells through specialised molecules of the cell surface. This process can occur either through direct contact between cell surfaces such as cell junctions or indirect interaction, where cells attach to surrounding extracellular matrix, a gel-like structure containing molecules released by cells into spaces between them. Cells adhesion occurs from the interactions between cell-adhesion molecules (CAMs), transmembrane proteins located on the cell surface.

Cell adhesion molecule

Cell adhesion molecules (CAMs) are a subset of cell surface proteins that are involved in the binding of cells with other cells or with the extracellular matrix (ECM), in a process called cell adhesion. In essence, CAMs help cells stick to each other and to their surroundings. CAMs are crucial components in maintaining tissue structure and function. In fully developed animals, these molecules play an integral role in generating force and movement and consequently ensuring that organs are able to execute their functions normally.

Contractile vacuole

A contractile vacuole (CV) is a sub-cellular structure (organelle) involved in osmoregulation. It is found predominantly in protists and in unicellular algae. It was previously known as pulsatile or pulsating vacuole. The contractile vacuole is a specialized type of vacuole that regulates the quantity of water inside a cell. In freshwater environments, the concentration of solutes is hypotonic, lower outside than inside the cell. Under these conditions, osmosis causes water to accumulate in the cell from the external environment.

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