Bio-inspired self-organizing cellular systems

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The present invention relates to systems and methods for predicting a prognosis of the neuropsychological and/or neuropsychiatric status in a subject based on reports of Minor Hallucination (MH) events in combination with electrophysiological data of the s ...

Predicting the evolution of systems with spatio-temporal dynamics in response to external stimuli is essential for scientific progress. Traditional equations-based approaches leverage first principles through the numerical approximation of differential equ ...

We study the problem of learning unknown parameters in stochastic interacting particle systems with polynomial drift, interaction, and diffusion functions from the path of one single particle in the system. Our estimator is obtained by solving a linear sys ...

One of the goals of synthetic biology is the development of an artificial cell. Building an artificial cell from scratch will provide a deeper understanding of fundamental mechanisms and models in biology and promises to contribute towards building novel p ...

Base excision repair enzymes (BERs) detect and repair oxidative DNA damage with efficacy despite the small size of the defects and their often only minor structural impact. A charge transfer (CT) model for rapid scanning of DNA stretches has been evoked to ...

The rapid development of wearable biomedical systems now enables real-time monitoring of electroencephalography (EEG) signals. Acquisition of these signals relies on electrodes. These systems must meet the design challenge of selecting an optimal set of el ...

Interacting particle systems play a key role in science and engineering. Access to the governing particle interaction law is fundamental for a complete understanding of such systems. However, the inherent system complexity keeps the particle interaction hi ...

Biomimetic retinas with a wide field of view and high resolution are in demand for neuroprosthetics and robot vision. Conventional neural prostheses are manufactured outside the application area and implanted as a complete device using invasive surgery. He ...

Telomeres are nucleoprotein structures at the ends of linear chromosomes, being essential for the maintenance of genomic integrity. Telomeres have a unique structure which distinguishes chromosome termini from DNA damage sites. Shelterin complexes are the ...

Systems and methods for monitoring penile tumescence are provided that overcome the drawbacks of previously known systems by providing a wearable formed of a flexible and elastic tube having a plurality of sensors disposed on or embedded within it, the wea ...

The Spindle Assembly Abnormal Protein 6 (SAS-6) forms dimers, which then self-assemble into rings that are critical for the nine-fold symmetry of the centriole organelle. It has recently been shown experimentally that the self-assembly of SAS-6 rings is st ...

We study socio-political systems in representative democracies. Motivated by problems that affect the proper functioning of the system, we build computational methods to answer research questions regarding the phenomena occurring in them. For each phenomen ...

While software applications, programming languages, and hardware have changed, operating systems have not. Widely-used commodity operating systems are still modeled after the ones designed in the seventies. The accumulated burden of backward compatibility ...

While systems designers are increasingly turning to hardware accelerators for performance gains, realizing these gains is painstaking and error-prone. It can take several person-months to determine if a given accelerator is a good fit for a given piece of ...

Imaging diagnostics in Joint European Torus have become essential in the study of plasma wall interactions and the protection of the plasma facing components. During deuterium operations, the location of these diagnostics was at close proximity to the vess ...

The discretization of robust quadratic optimal control problems under uncertainty using the finite element method and the stochastic collocation method leads to large saddle-point systems, which are fully coupled across the random realizations. Despite its ...

TAR DNA-binding protein with 43 kD (TDP-43) is a partially disordered protein that misfolds and accumulates in the brains of patients affected by several neurodegenerative diseases. TDP-43 oligomers have been reported to form due to aberrant misfolding or ...

Why biological quality-control systems fail is often mysterious. Specifically, checkpoints such as the DNA damage checkpoint or the spindle assembly checkpoint are overriden after prolonged arrests allowing cells to continue dividing despite the continued ...

Artificial intelligence (AI) plays a rapidly increasing role in clinical care. Many of these systems, for instance, deep learning-based applications using multilayered Artificial Neural Nets, exhibit epistemic opacity in the sense that they preclude compre ...

Cellulose nanocrystal (CNC) suspensions can self-assemble into chiral nematic films upon the slow evaporation of water. These films are brittle, as indicated by their fracturing instead of plastically deforming once they are fully elastically deformed. Thi ...

Bio-inspired self-organizing cellular systems

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System for predicting a prognosis of the neuropsychological and/or neuropsychiatric status in a subject

Learning the intrinsic dynamics of spatio-temporal processes through Latent Dynamics Networks

A Method of Moments Estimator for Interacting Particle Systems and their Mean Field Limit

Advancing Cell-Free Synthetic Biology: From sustained PURE protein synthesis to an isothermal one-pot DNA replication system

Oxidative Defect Detection Within Free and Packed DNA Systems: A Quantum Mechanical/Molecular Mechanics (QM/ MM) Approach

FETCH: A Fast and Efficient Technique for Channel Selection in EEG Wearable Systems

Learning Physics-Consistent Particle Interactions

Colloidal self-assembly of soft neural interfaces from injectable photovoltaic microdevices

Telomere protection against oxidative stress

Tumescense monitoring system for diagnosing erectile dysfunction and methods of use

Grand canonical Brownian dynamics simulations of adsorption and self-assembly of SAS-6 rings on a surface

How Words Move Hearts: Interpretable Machine Learning Models of Bias, Engagement, and Influence in Socio-Political Systems

Dynamic Linkers Are the Narrow Waist of Operating Systems

The Case for Performance Interfaces for Hardware Accelerators

Remote wide angle view broad wavelength viewing system compatible with D-T operations in JET

Preconditioners for robust optimal control problems under uncertainty

Recombinant Full-Length TDP-43 Oligomers Retain Their Ability to Bind RNAs, Are Not Toxic, and Do Not Seed TDP-43 Aggregation in Vitro

Principles of checkpoint override

Misplaced Trust and Distrust: How Not to Engage with Medical Artificial Intelligence

Design of experiments to investigate multi-additive cellulose nanocrystal films