Publication

Breaking down IgA: Tomasiella immunophila enlightens microbiome–immune interactions

Duncan-Bruce Sutherland
2024

Abstract

The recent discovery by Lu and colleagues of Tomasiella immunophila, a bacterium that degrades IgA, offers insights into microbial influences on mucosal immunity and evolutionary immune trade-offs. By modulating IgA titers, T. immunophila influences the dynamic interactions and balance between the host and pathogen. This has implications for immune health, microbiome research, and therapeutics.

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Breaking down IgA: Tomasiella immunophila enlightens microbiome–immune interactions

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