Publications related to Clinical value of assessing motor performance in postacute stroke patients

Immersive VR for upper-extremity rehabilitation in patients with neurological disorders: a scoping review

Background Neurological disorders, such as stroke and chronic pain syndromes, profoundly impact independence and quality of life, especially when affecting upper extremity (UE) function. While conventional physical therapy has shown effectiveness in provid ...

BioMed Central2024

An objective skill assessment framework for microsurgical anastomosis based on ALI scores

Aude Billard, Anaëlle Olivia Marie Manon, Kunpeng Yao, Soheil Gholami, Torstein Ragnar Meling

IntroductionThe current assessment and standardization of microsurgical skills are subjective, posing challenges in reliable skill evaluation. We aim to address these limitations by developing a quantitative and objective framework for accurately assessing ...

Springer Wien2024

A comprehensive stroke risk assessment by combining atrial computational fluid dynamics simulations and functional patient data

Alfio Quarteroni

Stroke, a major global health concern often rooted in cardiac dynamics, demands precise risk evaluation for targeted intervention. Current risk models, like the CHA 2 DS 2 -VASc \documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepa ...

Nature Portfolio2024

Non-invasive stimulation of the human striatum disrupts reinforcement learning of motor skills

Elena Beanato, Esra Neufeld, Friedhelm Christoph Hummel, Takuya Morishita, Maximilian Jonas Wessel, Traian Popa, Pierre Theopistos Vassiliadis, Julie Duqué, Fabienne Windel

Reinforcement feedback can improve motor learning, but the underlying brain mechanisms remain underexplored. In particular, the causal contribution of specific patterns of oscillatory activity within the human striatum is unknown. To address this question, ...

Nature Portfolio2024

Context-Aware Monitoring of Hand Motor Primitives in Daily Life Activities: A Pathway to Objectively Assess Rehabilitation of Patients with Upper-Limb Neurological Impairment

The hands, our silent performers in daily life, face overwhelming challenges when neurological impairments disrupt the simple tasks that compose our daily symphony. This thesis unveils a comprehensive framework for the objective monitoring of upper-limb re ...

EPFL2024

Accelerometry as a tool for measuring the effects of transcranial magnetic stimulation

Pierre Theopistos Vassiliadis, Julie Duqué

Objective: We predicted that accelerometry would be a viable alternative to electromyography (EMG) for assessing fundamental Transcranial Magnetic Stimulation (TMS) measurements (e.g. Resting Motor Threshold (RMT), recruitment curves, latencies). New Metho ...

Elsevier2024

Trio preserves motor synapses and prolongs motor ability during aging

Evelyne Ruchti, Greta Limoni, Brian Donal McCabe, Wei Jiao, Soumya Banerjee, Samuel William Vernon

The decline of motor ability is a hallmark feature of aging and is accompanied by degeneration of motor synaptic terminals. Consistent with this, Drosophila motor synapses undergo characteristic age -dependent structural fragmentation co -incident with dim ...

Cell Press2024

Augmenting locomotor perception by remapping tactile foot sensation to the back

Mohamed Bouri, Olaf Blanke, Oliver Alan Kannape, Atena Fadaeijouybari, Selim Jean Habiby Alaoui

Background :Sensory reafferents are crucial to correct our posture and movements, both reflexively and in a cognitively driven manner. They are also integral to developing and maintaining a sense of agency for our actions. In cases of compromised reafferen ...

BioMed Central2024

The mouse motor system contains multiple premotor areas and partially follows human

Joanes Grandjean, Valerio Zerbi

While humans are known to have several premotor cortical areas, secondary motor cortex (M2) is often considered to be the only higher -order motor area of the mouse brain and is thought to combine properties of various human premotor cortices. Here, we sho ...

Cell Press2024

Uncovering interactions between Descending Neurons as a functional principle of behavioural control

Jonas Friedrich Braun

Animals, including humans, exhibit a remarkable variety of complex behaviours. How the nervous system controls all these behaviours ranging from simple, stereotyped movements to flexible, adaptive actions is a central questions of neuroscience. One of the ...

EPFL2024

The role of computational methods in cardiovascular medicine: a narrative review

Alfio Quarteroni, Luca Dede', Christian Vergara, Stefano Pagani

Background and Objective: Computational models of the cardiovascular system allow for a detailed and quantitative investigation of both physiological and pathological conditions, thanks to their ability to combine clinical-possibly patient-specific-data wi ...

Ame Publishing Company2024

Efficacy and safety of transcranial direct current stimulation to the ipsilesional motor cortex in subacute stroke (NETS): a multicenter, randomized, double-blind, placebo-controlled trial

Friedhelm Christoph Hummel

Background Each year, five million people are left disabled after stroke. Upper -extremity (UE) dysfunction is a leading problem. Neuroplasticity can be enhanced by non-invasive brain stimulation (NIBS) but evidence from large, randomized multicenter trial ...

Elsevier2024

Probing and modulating inter-areal coupling in the cortical visual motion processing pathway with non-invasive brain stimulation

Michele Bevilacqua

In the last few years, stroke ranked as the second most common cause of death and is the third most significant condition affecting disability-adjusted life years (DALYs) worldwide. Being the most prevalent and quality of life impacting post-stroke symptom ...

EPFL2024

High energy-density electrostatic actuators for soft robotics

Sylvain Thomas Schaller

This thesis reports high energy-density electrostatic actuators for use in soft robotics. This thesis has two main parts: a) a detailed study of electro-adhesion using microfabricated electrodes, and b) a flexi-ble fiber-shaped linear motor. Electro-adhesi ...

EPFL2024

Combination of Neurotechnologies Towards Personalized Neurorehabilitation for Stroke Patients

Claudia Bigoni

"Ensure healthy lives and promote well-being for all at all ages" is the third sustainable development goal for the United Nations Agenda of 2030. This doctoral thesis fully embodied this objective by targeting stroke, a leading cause of death and disabili ...

EPFL2023

Neurophysiological underpinnings of an intensive protocol for upper limb motor recovery in subacute and chronic stroke patients

Silvestro Micera, Matteo Vissani, Michael Lassi

ABS T R A C T BACKGROUND: Upper limb (UL) motor impairment following stroke is a leading cause of functional limitations in activities of daily living. Robot-assisted therapy supports rehabilitation, but how its efficacy and the underlying neural mechanism ...

Edizioni Minerva Medica2023

Neuronal correlates of goal-directed sensorimotor transformation in sensory, motor and higher-order cortical areas

Anastasiia Oryshchuk

An important function of the brain is to interpret incoming sensory information from the outside world to guide adaptive behavior. Understanding how and where sensory information is transformed into motor commands in a context- and learning-dependent manne ...

EPFL2023

Prediction of post-stroke motor recovery benefits from measures of sub-acute widespread network damages

Dimitri Nestor Alice Van De Ville, Elvira Pirondini, Maria Giulia Preti, Cyprien Alban Félicien Rivier

Rivier et al. report that global measures of brain connectivity estimated by introducing virtual lesions in healthy structural connectomes significantly increase the accuracy of motor recovery prediction in stroke patients when added to focal and clinical ...

OXFORD UNIV PRESS2023

Early motor skill acquisition in healthy older adults: brain correlates of the learning process

Manon Chloé Durand-Ruel, Pablo Maceira Elvira, Friedhelm Christoph Hummel, Takuya Morishita, Maeva Moyne, Chang-Hyun Park

Motor skill learning is a crucial process at all ages. However, healthy aging is often accompanied by a reduction in motor learning capabilities. This study characterized the brain dynamics of healthy older adults during motor skill acquisition and identif ...

OXFORD UNIV PRESS INC2023

Motor imagery training to improve language processing: What are the arguments?

Sylvain Jean-François Harquel

Studies showed that motor expertise was found to induce improvement in language processing. Grounded and situated approaches attributed this effect to an underlying automatic simulation of the motor experience elicited by action words, similar to motor ima ...

FRONTIERS MEDIA SA2023