Publication

Low-dose photodynamic therapy promotes a cytotoxic immunological response in a murine model of pleural mesothelioma

Paul Joseph Dyson, Etienne Meylan, Julien Robert Rémi Faget, Aspasia Gkasti, Yameng Hao
2020
Journal Articles

Abstract

OBJECTIVES: Malignant pleural mesothelioma (MPM) is a deadly disease with limited treatment options. Approaches to enhance patient immunity against MPM have been tested but shown variable results. Previously, we have demonstrated interesting vascular modulating properties of low-dose photodynamic therapy (L-PDT) on MPM. Here, we hypothesized that L-PDT vascular modulation could favour immune cell extravasation in MPM and improve tumour control in combination with immune checkpoint inhibitors.

Official source

https://infoscience.epfl.ch/entities/publication/113c2fa3-863a-43ae-a661-166e34198db6

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Low-dose photodynamic therapy promotes a cytotoxic immunological response in a murine model of pleural mesothelioma

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