Irradiation in a flash: Unique sparing of memory in mice after whole brain irradiation with dose rates above 100 Gy/s

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A theory of memory consolidation and synaptic pruning in cortical circuits

Georgios Iatropoulos

Over the course of a lifetime, the human brain acquires an astonishing amount of semantic knowledge and autobiographical memories, often with an imprinting strong enough to allow detailed information to be recalled many years after the initial learning exp ...

EPFL2023

Chaosity: Understanding Contemporary NUMA-architectures

Andreea Nica, Anastasia Ailamaki, Viktor Sanca, Syed Mohammad Aunn Raza, Hamish Mcniece Hill Nicholson

Modern hardware is increasingly complex, requiring increasing effort to understand in order to carefully engineer systems for optimal performance and effective utilization. Moreover, established design principles and assumptions are not portable to modern ...

2023

Toward contactless human thermal monitoring: A framework for Machine Learning-based human thermo-physiology modeling augmented with computer vision

Alexandre Massoud Alahi, Dolaana Khovalyg, Mohamad Rida, Mohamed Ossama Ahmed Abdelfattah

The transition towards a human-centered indoor climate is beneficial from occupants’ thermal comfort and from an energy reduction perspective. However, achieving this goal requires the knowledge of the thermal state of individuals at the level of body part ...

2023

Hydrogenated amorphous silicon high flux x-ray detectors for synchrotron microbeam radiation therapy

Nicolas Würsch, Sylvain Dunand

Objective. Microbeam radiation therapy (MRT) is an alternative emerging radiotherapy treatment modality which has demonstrated effective radioresistant tumour control while sparing surrounding healthy tissue in preclinical trials. This apparent selectivity ...

IOP Publishing Ltd2023

The effects of visual distractors on serial dependence

David Pascucci

Attractive serial dependence occurs when perceptual decisions are attracted toward previous stimuli. This effect is mediated by spatial attention and is most likely to occur when similar stimuli are attended at nearby locations. Attention, however, also in ...

Association for Research in Vision and Ophthalmology (ARVO)2023

Corpus callosum structural characteristics in very preterm children and adolescents: Developmental trajectory and relationship to cognitive functioning

Dimitri Nestor Alice Van De Ville, Lorena Gonçalves de Alcântara e Freitas Krikler, Vanessa Siffredi

Previous studies suggest that structural alteration of the corpus callosum, i.e., the largest white matter commissural pathway, occurs after a preterm birth in the neonatal period and lasts across development. The present study aims to unravel corpus callo ...

ELSEVIER SCI LTD2023

Development of Visual Memory Capacity Following Early-Onset and Extended Blindness

Lukas Vogelsang

It is unknown whether visual memory capacity can develop if onset of pattern vision is delayed for several years following birth. We had an opportunity to address this question through our work with an unusual population of 12 congenitally blind individual ...

2022

Modulation of working memory duration by synaptic and astrocytic mechanisms

Sophia Becker

Short-term synaptic plasticity and modulations of the presynaptic vesicle release rate are key components of many working memory models. At the same time, an increasing number of studies suggests a potential role of astrocytes in modulating higher cognitiv ...

PUBLIC LIBRARY SCIENCE2022

Aesthetic experience enhances first-person spatial representation

Mariana Babo Rebelo

Episodic autobiographical memories are characterized by a spatial context and an affective component. But how do affective and spatial aspects interact? Does affect modulate the way we encode the spatial context of events? We investigated how one element o ...

National Academy of Sciences2022

Where does the engram come from? Study of prefrontal cortex inputs during memory consolidation

Lucie Pauline Dixsaut

The formation and storage of memories has been under deep investigation for several decades. Nevertheless, the precise contribution of each brain region involved in this process and the interplay between them across memory consolidation is still largely de ...

EPFL2022

Cognitive Impairment and Metabolite Profile Alterations in the Hippocampus and Cortex of Male and Female Mice Exposed to a Fat and Sugar-Rich Diet are Normalized by Diet Reversal

João Miguel das Neves Duarte, Adélaïde Alice Mohr

Diabetes impacts on brain metabolism, structure, and function. Alterations in brain metabolism have been observed in obesity and diabetes models induced by exposure to diets rich in saturated fat and/or sugar and have been linked to memory impairment. Howe ...

INT SOC AGING & DISEASE2022