Wnt signaling pathwayThe Wnt signaling pathways are a group of signal transduction pathways which begin with proteins that pass signals into a cell through cell surface receptors. The name Wnt is a portmanteau created from the names Wingless and Int-1. Wnt signaling pathways use either nearby cell-cell communication (paracrine) or same-cell communication (autocrine). They are highly evolutionarily conserved in animals, which means they are similar across animal species from fruit flies to humans.
HydrologyHydrology () is the scientific study of the movement, distribution, and management of water on Earth and other planets, including the water cycle, water resources, and drainage basin sustainability. A practitioner of hydrology is called a hydrologist. Hydrologists are scientists studying earth or environmental science, civil or environmental engineering, and physical geography. Using various analytical methods and scientific techniques, they collect and analyze data to help solve water related problems such as environmental preservation, natural disasters, and water management.
Notch signaling pathwayThe Notch signaling pathway is a highly conserved cell signaling system present in most animals. Mammals possess four different notch receptors, referred to as NOTCH1, NOTCH2, NOTCH3, and NOTCH4. The notch receptor is a single-pass transmembrane receptor protein. It is a hetero-oligomer composed of a large extracellular portion, which associates in a calcium-dependent, non-covalent interaction with a smaller piece of the notch protein composed of a short extracellular region, a single transmembrane-pass, and a small intracellular region.
Signal transductionSignal transduction is the process by which a chemical or physical signal is transmitted through a cell as a series of molecular events. Most commonly, protein phosphorylation is catalyzed by protein kinases, ultimately resulting in a cellular response. Proteins responsible for detecting stimuli are generally termed receptors, although in some cases the term sensor is used. The changes elicited by ligand binding (or signal sensing) in a receptor give rise to a biochemical cascade, which is a chain of biochemical events known as a signaling pathway.
Biochemical cascadeA biochemical cascade, also known as a signaling cascade or signaling pathway, is a series of chemical reactions that occur within a biological cell when initiated by a stimulus. This stimulus, known as a first messenger, acts on a receptor that is transduced to the cell interior through second messengers which amplify the signal and transfer it to effector molecules, causing the cell to respond to the initial stimulus. Most biochemical cascades are series of events, in which one event triggers the next, in a linear fashion.
Residence timeThe residence time of a fluid parcel is the total time that the parcel has spent inside a control volume (e.g.: a chemical reactor, a lake, a human body). The residence time of a set of parcels is quantified in terms of the frequency distribution of the residence time in the set, which is known as residence time distribution (RTD), or in terms of its average, known as mean residence time. Residence time plays an important role in chemistry and especially in environmental science and pharmacology.
TurbulenceIn fluid dynamics, turbulence or turbulent flow is fluid motion characterized by chaotic changes in pressure and flow velocity. It is in contrast to a laminar flow, which occurs when a fluid flows in parallel layers, with no disruption between those layers. Turbulence is commonly observed in everyday phenomena such as surf, fast flowing rivers, billowing storm clouds, or smoke from a chimney, and most fluid flows occurring in nature or created in engineering applications are turbulent.
Nuclear magnetic resonance spectroscopy of proteinsNuclear magnetic resonance spectroscopy of proteins (usually abbreviated protein NMR) is a field of structural biology in which NMR spectroscopy is used to obtain information about the structure and dynamics of proteins, and also nucleic acids, and their complexes. The field was pioneered by Richard R. Ernst and Kurt Wüthrich at the ETH, and by Ad Bax, Marius Clore, Angela Gronenborn at the NIH, and Gerhard Wagner at Harvard University, among others.
Atmospheric escapeAtmospheric escape is the loss of planetary atmospheric gases to outer space. A number of different mechanisms can be responsible for atmospheric escape; these processes can be divided into thermal escape, non-thermal (or suprathermal) escape, and impact erosion. The relative importance of each loss process depends on the planet's escape velocity, its atmosphere composition, and its distance from its star. Escape occurs when molecular kinetic energy overcomes gravitational energy; in other words, a molecule can escape when it is moving faster than the escape velocity of its planet.
Water cycleThe water cycle, also known as the hydrologic cycle or the hydrological cycle, is a biogeochemical cycle that describes the continuous movement of water on, above and below the surface of the Earth. The mass of water on Earth remains fairly constant over time but the partitioning of the water into the major reservoirs of ice, fresh water, saline water (salt water) and atmospheric water is variable depending on a wide range of climatic variables.
Drainage basinA drainage basin is an area of land where all flowing surface water converges to a single point, such as a river mouth, or flows into another body of water, such as a lake or ocean. A basin is separated from adjacent basins by a perimeter, the drainage divide, made up of a succession of elevated features, such as ridges and hills. A basin may consist of smaller basins that merge at river confluences, forming a hierarchical pattern. Other terms for a drainage basin are catchment area, catchment basin, drainage area, river basin, water basin, and impluvium.
Nuclear Overhauser effectThe nuclear Overhauser effect (NOE) is the transfer of nuclear spin polarization from one population of spin-active nuclei (e.g. 1H, 13C, 15N etc.) to another via cross-relaxation. A phenomenological definition of the NOE in nuclear magnetic resonance spectroscopy (NMR) is the change in the integrated intensity (positive or negative) of one NMR resonance that occurs when another is saturated by irradiation with an RF field. The change in resonance intensity of a nucleus is a consequence of the nucleus being close in space to those directly affected by the RF perturbation.
Exact solutions in general relativityIn general relativity, an exact solution is a solution of the Einstein field equations whose derivation does not invoke simplifying assumptions, though the starting point for that derivation may be an idealized case like a perfectly spherical shape of matter. Mathematically, finding an exact solution means finding a Lorentzian manifold equipped with tensor fields modeling states of ordinary matter, such as a fluid, or classical non-gravitational fields such as the electromagnetic field.
FluxFlux describes any effect that appears to pass or travel (whether it actually moves or not) through a surface or substance. Flux is a concept in applied mathematics and vector calculus which has many applications to physics. For transport phenomena, flux is a vector quantity, describing the magnitude and direction of the flow of a substance or property. In vector calculus flux is a scalar quantity, defined as the surface integral of the perpendicular component of a vector field over a surface.
Gödel metricThe Gödel metric, also known as the Gödel solution or Gödel universe, is an exact solution of the Einstein field equations in which the stress–energy tensor contains two terms, the first representing the matter density of a homogeneous distribution of swirling dust particles (dust solution), and the second associated with a negative cosmological constant (see Lambdavacuum solution). This solution has many unusual properties—in particular, the existence of closed time-like curves that would allow time travel in a universe described by the solution.
Eddy covarianceThe eddy covariance (also known as eddy correlation and eddy flux) is a key atmospheric measurement technique to measure and calculate vertical turbulent fluxes within atmospheric boundary layers. The method analyses high-frequency wind and scalar atmospheric data series, gas, energy, and momentum, which yields values of fluxes of these properties. It is a statistical method used in meteorology and other applications (micrometeorology, oceanography, hydrology, agricultural sciences, industrial and regulatory applications, etc.
Escape velocityIn celestial mechanics, escape velocity or escape speed is the minimum speed needed for a free, non-propelled object to escape from the gravitational influence of a primary body, thus reaching an infinite distance from it. It is typically stated as an ideal speed, ignoring atmospheric friction. Although the term "escape velocity" is common, it is more accurately described as a speed than a velocity because it is independent of direction.
