Electronic clinical decision support algorithms (CDSAs) have been developed to address high childhood mortality and inappropriate antibiotic prescription by helping clinicians adhere to guidelines. Previously identified challenges of CDSAs include their li ...
Mitohormesis defines the increase in fitness mediated by adaptive responses to mild mitochondrial stress. Tetracyclines inhibit not only bacterial but also mitochondrial translation, thus imposing a low level of mitochondrial stress on eukaryotic cells. We ...
Antimicrobial peptides (AMPs) are host-encoded antibiotics that combat invading pathogens. These genes commonly encode multiple products as post-translationally cleaved polypeptides. Recent studies have highlighted roles for AMPs in neurological contexts s ...
The design, synthesis, fundamentals and evaluation of 2D/3D antimicrobial surfaces are addressed in detail in the current review. Recent advances in the antimicrobial mechanism, kinetics and properties of Ag, Cu and Ag-Cu surfaces in the dark and under lig ...
Invisible to the human eye, yet ubiquitous... The occurrence and the potential adverse effects of micropollutants in the environment are uncontested. Due to incomplete removal by conventional wastewater treatment technologies, the aquatic environment is co ...
This review describes the design, synthesis and evaluation of novel catechol based anchors for surface modification. The anachelin chromophore, the catecholate fragment of the siderophore anachelin from the cyanobacterium Anabaena cylindrica, allows for th ...
Phenotypic heterogeneity, defined as metastable variation in cellular parameters generated by epigenetic mechanisms, is crucial for the persistence of bacterial populations under fluctuating selective pressures. Diversity ensures that some individuals will ...
