Pharmacological stimulation to facilitate and restore standing and walking functions in spinal cord motor disorders

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A low-power digital charge balancing system, which ensures the safe operation of constant-current biphasic stimulation is presented. The concept of the proposed charge-balancing technique is to utilize a hybrid method consisting of anodic pulse modulation ...

Objective. Peripheral nerve interfaces have the potential to restore sensory, motor, and visceral functions. In particular, intraneural interfaces allow targeting deep neural structures with high selectivity, even if their performance strongly depends upon ...

Spinal Cord Injury (SCI) results in damage to neural circuitry connecting the brain to the periphery. Consequently, sensory and motor function is lost, to varying degree, depending on the site and severity of the lesion. More than half of spinal cord injur ...

The authors summarize changes in circuits after spinal cord injury and current strategies to target these circuits in order to improve recovery, but also advocate for new concepts of reorganizing circuits informed by multi-omic single-cell atlases. ...

Objective. Meralgia paresthetica (MP) is a mononeuropathy of the exclusively sensory lateral femoral cutaneous nerve (LFCN) that is difficult to treat with conservative treatments. Afferents from the LFCN enter the spinal cord through the dorsal root entry ...

In the last decades, clinical neuroscience found a novel ally in neurotechnologies, devices able to record and stimulate electrical activity in the nervous system. These technologies improved the ability to diagnose and treat neural disorders. Neurotechnol ...

Transcranial (electro)magnetic stimulation (TMS) is currently the method of choice to non-invasively induce neural activity in the human brain. A single transcranial stimulus induces a time-varying electric field in the brain that may evoke action potentia ...

The auditory brainstem implant (ABI) is an auditory neuroprosthesis that provides hearing to deaf patients by electrically stimulating the cochlear nucleus (CN) of the brainstem. Whether such stimulation activates one or the other of the CN's two major sub ...

Prism Adaptation (PA) is a useful method to study the mechanisms of sensorimotor adaptation. After-effects following adaptation to the prismatic deviation constitute the probe that adaptive mechanisms occurred, and current evidence suggests an involvement ...

The use of TMS-EEG coupling as a neuroimaging tool for the functional exploration of the human brain recently gained strong interest. If this tool directly inherits the fine temporal resolution from EEG, its spatial counterpart remains unknown. In this stu ...

The acquisition and re-acquisition of motor skills is an important aspect of daily life and in the recovery after a stroke. Non-invasive brain stimulation (NIBS) is a technique that is used to improve motor learning and enhance motor recovery in stroke sur ...

Pharmacological stimulation to facilitate and restore standing and walking functions in spinal cord motor disorders

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Digital One-Shot Charge-balancing Method for Implantable Current-Mode Electrical Stimulation

Combining biophysical models and machine learning to optimize implant geometry and stimulation protocol for intraneural electrodes

Sensor-based control strategies for integration of epidural electrical stimulation in rehabilitation after spinal cord injury

Natural and targeted circuit reorganization after spinal cord injury

Targeted dorsal root entry zone stimulation alleviates pain due to meralgia paresthetica

Clinical neuroscience and neurotechnology: An amazing symbiosis

Transcranial magnetic stimulation of the brain: What is stimulated? - A consensus and critical position paper

Comparison of Responses to DCN vs. VCN Stimulation in a Mouse Model of the Auditory Brainstem Implant (ABI)

Does anodal cerebellar tDCS boost transfer of after-effects from throwing to pointing during prism adaptation?

Exploring the spatial resolution of TMS-EEG coupling on the sensorimotor region

Does one size fit all? - Towards the optimization and personalization of non-invasive brain stimulation paradigms to enhance motor learning