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We review unitarity and crossing constraints on scattering amplitudes for particles with spin in four dimensional quantum field theories. As an application we study two to two scattering of neutral spin 1/2 fermions in detail. Assuming Mandelstam analyticity of its scattering amplitude, we use the numerical S-matrix bootstrap method to estimate various non-perturbative bounds on quartic and cubic (Yukawa) couplings.
Mark Pauly, Quentin Christian Becker