Publication

Temperature effect on connective tissue cells

2012
Student Projects

Abstract

Intervertebral discs (IVD) are soft tissues that have viscoelastic behavior. Under cyclic loading, viscoelastic tissues dissipate the mechanical loading through the production of heat. In IVD, it is hypothesized that heat cannot be convected from the nucleus pulposus (NP), since it is not perfused by the cardio-vascular system. This may result in local increase of temperature in the NP, and therefore may affect the metabolism of cells present in NP or its mechanical behavior. The overall goal of the project is to study the only thermal contribution on NP cells metabolism, without any mechanical effect. A screening of potential effects, due to different temperatures, will be performed on fetal cells and on cells extracted from bovine NP.

Official source

https://infoscience.epfl.ch/entities/publication/0d46a0c1-c503-4fe3-b2dc-74195f4c8316

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2012
Student Projects

Abstract

Official source

https://infoscience.epfl.ch/entities/publication/0d46a0c1-c503-4fe3-b2dc-74195f4c8316

About this result

Related concepts (32)

Temperature

Temperature is a physical quantity that expresses quantitatively the perceptions of hotness and coldness. Temperature is measured with a thermometer. Thermometers are calibrated in various temperature scales that historically have relied on various reference points and thermometric substances for definition. The most common scales are the Celsius scale with the unit symbol °C (formerly called centigrade), the Fahrenheit scale (°F), and the Kelvin scale (K), the latter being used predominantly for scientific purposes.

Viscoelasticity

In materials science and continuum mechanics, viscoelasticity is the property of materials that exhibit both viscous and elastic characteristics when undergoing deformation. Viscous materials, like water, resist shear flow and strain linearly with time when a stress is applied. Elastic materials strain when stretched and immediately return to their original state once the stress is removed. Viscoelastic materials have elements of both of these properties and, as such, exhibit time-dependent strain.

Heat

In thermodynamics, heat is the thermal energy transferred between systems due to a temperature difference. In colloquial use, heat sometimes refers to thermal energy itself. An example of formal vs. informal usage may be obtained from the right-hand photo, in which the metal bar is "conducting heat" from its hot end to its cold end, but if the metal bar is considered a thermodynamic system, then the energy flowing within the metal bar is called internal energy, not heat.

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Temperature effect on connective tissue cells

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