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Alternative splicing, an unknown mechanism 20 years ago, is now recognized as a major mechanism for proteome and transcriptome diversity, particularly in mammals-some researchers conjecture that up to 90% of human genes are alternatively spliced. Despite much research on exon and intron evolution, little is known about the evolution of transcripts.
Sahand Jamal Rahi, Vojislav Gligorovski, Marco Labagnara, Lazar Stojkovic, Mahsa Geramimanesh
Didier Trono, Evaristo José Planet Letschert, Wayo Matsushima