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This article describes four fluorescent membrane tension probes that have been designed, synthesized, evaluated, commercialized and applied to current biology challenges in the context of the NCCR Chemical Biology. Their names are Flipper-TR (R), ER Flipper-TR (R), Lyso Flipper-TR (R), and Mito Flipper-TR (R). They are available from Spirochrome.
Edoardo Charbon, Claudio Bruschini
Jérôme Waser, Aleksandra Radenovic, Beat Fierz, Nathan Cyprien Arsène Ronceray, Xingyu Liu, Wei Cai