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Asymmetric cell division is fundamental for generating diversity in multicellular organisms. The mechanisms that govern asymmetric cell division are increasingly well understood, owing notably to studies that were conducted in Drosophila melanogaster and Caenorhabditis elegans. Lessons learned from these two model organisms also apply to cells that divide asymmetrically in other metazoans, such as self-renewing stem cells in mammals
Johan Auwerx, Huyen Thuc Tran Luong
Douglas Hanahan, Mélanie Louise Tichet, Elizabeth Anne Allen, Ke Cheng