Publication

Synthesis, characterisation and in vitro anticancer activity of hexanuclear thiolato-bridged arene ruthenium metallaprisms

Paul Joseph Dyson, Catherine Marie Amélie Clavel
2013
Journal Articles

Abstract

Hexanuclear thiolato-bridged arene ruthenium metalla-prisms of the general formula [(p-cymene)6Ru6(SR)6(tpt)2]6+ (R=CH2Ph, CH2C6H4-p-tBu, CH2CH2Ph; tpt=2,4,6-tris(4-pyridyl)-1,3,5-triazine), obtained from the dinuclear precursors [(p-cymene)2Ru2(SR)2Cl2], AgCF3SO3 and tpt, have been isolated and fully characterised as triflate salts. The metalla-prisms are highly cytotoxic against human ovarian cancer cells, especially towards the cisplatin-resistant cell line A2780cisR (IC50

Official source

https://infoscience.epfl.ch/entities/publication/044cf83c-1876-4cc9-9f3f-5680aae41a83

About this result

This page is automatically generated and may contain information that is not correct, complete, up-to-date, or relevant to your search query. The same applies to every other page on this website. Please make sure to verify the information with EPFL's official sources.

Graph Chat

Chat with Graph Search

Ask any question about EPFL courses, lectures, exercises, research, news, etc. or try the example questions below.

DISCLAIMER: The Graph Chatbot is not programmed to provide explicit or categorical answers to your questions. Rather, it transforms your questions into API requests that are distributed across the various IT services officially administered by EPFL. Its purpose is solely to collect and recommend relevant references to content that you can explore to help you answer your questions.

Synthesis, characterisation and in vitro anticancer activity of hexanuclear thiolato-bridged arene ruthenium metallaprisms

Chat with Graph Search

Nanomotion-Based Drug Sensitivity Prediction in Ovarian and Colon Cancer Cell Lines Using Machine Learning

Nitride protonation and NH3 binding versus N-H bond cleavage in uranium nitrides

Palladium(II)-Stabilized Pyridine-2-Diazotates: Synthesis, Structural Characterization, and Cytotoxicity Studies