This thesis delves into the critical study of particle transport in matter, particularly emphasising
its implications for machine protection at CERN's accelerator complex and facilities. To conduct
studies of this nature, FLUKA and Geant4 stand out within ...
A spinal cord injury (SCI) triggers a cascade of molecular and cellular responses involving inflammatory cell infiltration and cytokine release, apoptosis, demyelination, excitotoxicity, ischemia, and the formation of a fibrotic scar surrounded by an astro ...
Formally verifying the correctness of software is necessary to merit the trust people put in software systems. Currently, formal verification requires human effort to prove that a piece of code matches its specification and code changes to improve verifiab ...
Historically speaking, the notion of the type was reintroduced to the larger architectural discourse as a direct consequence of the crisis of the Modern. The task of revisiting the forms of the past also dictated the return of architectural methods that ha ...
A metaprogrammer should be able to reason about the semantics of the generated code.
Multi-stage programming introduced an elegant and powerful solution to this problem.
It follows a semantically driven approach to code generation, where semantics are full ...
Activin-A is a Transforming Growth Factor-B (TGFB)-related cytokine that regulates various biological processes including cell proliferation and differentiation through autocrine, paracrine or endocrine signaling. Activin-A expression is upregulated in mul ...
Concepts of type and typology are not specific to architecture. Rather they represent an interdisciplinary approach to ordering knowledge and gaining insight. In the field of architecture, the study of types and typology offers a didactic perspective that ...
The widespread use of bots to support software development makes social coding platforms such as GitHub a particularly rich source of data for the study of human-bot interaction. Software development bots are used to automate repetitive tasks, interacting ...
It is generally assumed that the parent-twin interface is a fully invariant plane. The calculations of the rational interfaces of the type I twins and irrational interfaces of the type II twins are based on this hypothesis. Recently, some asymmetric facets ...
Over the past decade, the Scala community has shown great interest in using type-level programming to obtain additional type safety.
Unfortunately, the lack of support from the Scala compiler has been a barrier to the adoption of that technique, notably du ...
Although it has been nearly two and half decades since the discovery of alpha-synuclein (aSyn) as the major component of Lewy bodies (LBs), our understanding of the involvement of different aSyn species, their seeding, spreading and toxicity in Parkinson's ...
Since the birth of Information Theory, researchers have defined and exploited various information measures, as well as endowed them with operational meanings. Some were born as a "solution to a problem", like Shannon's Entropy and Mutual Information. Other ...
The North American construction industry has seen substantial growth in the use of cold-formed steel (CFS) framing for midrise buildings in recent years. In seismic zones, CFS-framed buildings utilize shear walls to provide the primary lateral resistance t ...
Locally correctable codes (LCCs) are error correcting codes C : \Sigmak \rightarrow \Sigman which admit local algorithms that correct any individual symbol of a corrupted codeword via a minuscule number of queries. For systematic codes, this notion is stro ...
In the first chapter of this thesis, the macrocyclization of a new type of bifunctional substrates, omega-isocyanoaldehyde derivatives, is described. Ten different omega-isocyanoaldehydes in terms of different ring sizes and functional groups were prepared ...
The current pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has affected most of the world in a profound way. As an indirect consequence, the general public has been put into direct contact with the research process, almost ...
In recent years, the idea that the prediction of sensory input is one of the major computational goals of the nervous system led to the development of several large-scale theories of brain functioning, such as different versions of the Bayesian approach to ...
This thesis develops novel multi-degrees-of-freedom flexure-based force sensors by exploiting white light interferometry. Fabry-Pérot interferometry measurement has nanometric accuracy which yields sub milli-Newton force sensing accuracy. Such force sensin ...
The crystallography of twinning is based on the concepts of simple shear and obliquity introduced by Mugge, Mallard and Friedel at the turn of the last century, with tensor mathematics later developed by Bilby, Bevis and Crocker in the 1960s. We propose a ...
In this work we give optimal, i.e., necessary and sufficient, conditions for integrals of the calculus of variations to guarantee the existence of solutions-both weak and variational solutions-to the associated L-2-gradient flow. The initial values are mer ...