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Uttam Dhawa

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Related publications (4)

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Copper-Catalyzed Benzylic Functionalization of Lignin-Derived Monomers

Arthur Blumenstein, Xile Hu, Uttam Dhawa, Lara Lavrencic

Within the field of lignin biorefining, significant research effort has been dedicated to the advancement of catalytic methods for lignocellulose depolymerization. However, another key challenge in lignin valorization is the conversion of the obtained mono ...

WILEY-V C H VERLAG GMBH2023

Enantioconvergent Cobalt‐Catalyzed Hydroalkylation for the Construction of Fluoro‐, Chloro‐, and Trifluoromethyl Stereogenic Centers

Xile Hu, Uttam Dhawa

Organic compounds containing a chiral, halogenated aliphatic carbon center are useful in medicinal chemistry, but their enantioselective synthesis remains difficult. Here we develop a general approach to access these compounds through cobalt‐catalyzed hydr ...

Wiley2025

Regiodivergent and Enantioselective Synthesis of Cyclic Sulfones via Ligand-Controlled Nickel-Catalyzed Hydroalkylation

Jennifer Morel, Xile Hu, Chao Fan, Uttam Dhawa, Deyun Qian

Cyclic sulfones have demonstrated important applications in drug discovery. However, the catalytic and enantioselective synthesis of chiral cyclic sulfones remains challenging. Herein, we develop nickel-catalyzed regiodivergent and enantioselective hydroal ...

Wiley-VCH Verlag GmbH2024

Nickel-Catalyzed Enantio- and Diastereoselective Synthesis of Fluorine-Containing Vicinal Stereogenic Centers

Xile Hu, Uttam Dhawa, Lara Lavrencic

The construction of fluorinated architectures has been a topic of interest to medicinal chemists due to their unique ability to improve the pharmacokinetic properties of bioactive compounds. However, the stereoselective synthesis of fluoro-organic compound ...

2024