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Sujeet Pawar

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Related publications (4)

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Inhibition of influenza virus infection in mice by pulmonary administration of a spray dried antiviral drug

Francesco Stellacci, Aurélien Bornet, Paulo Henrique Jacob Silva, Sujeet Pawar

Increasing resistance to antiviral drugs approved for the treatment of influenza urges the development of novel compounds. Ideally, this should be complemented by a careful consideration of the administration route. 6′siallyllactosamine-functionalized β-cy ...

2024

Structure-Activity Relationship Studies of Glycosaminoglycan Mimetic Macrocycles Against Herpes

Cynthia Paloma Aigroz, Hien Tran Thi, Deepika Sardana, Anita Zucchi, Francesco Stellacci, Paulo Henrique Jacob Silva, Melis Özkan, Sujeet Pawar

The herpes simplex virus (HSV) is associated with serious conditions, such as encephalitis and blindness, and its infection is closely linked to significant vascular complications and coagulation issues, particularly in individuals with compromised immune ...

AMER CHEMICAL SOC2025

Benzene with Alkyl Chains Is a Universal Scaffold for Multivalent Virucidal Antivirals

Jay-Ar Bautista Dela Cruz, Francesco Stellacci, Paulo Henrique Jacob Silva, Matteo Gasbarri, Lixia Wei, Yong Zhu, Heyun Wang, Sujeet Pawar

Most viruses start their invasion by binding to glycoproteins' moieties on the cell surface (heparan sulfate proteoglycans [HSPG] or sialic acid [SA]). Antivirals mimicking these moieties multivalently are known as broad-spectrum multivalent entry inhibito ...

Amer Chemical Soc2024

Beyond the limiting gap length: peripheral nerve regeneration through implantable nerve guidance conduits

Silvestro Micera, Francesco Stellacci, Melis Özkan, Sujeet Pawar

Peripheral nerve damage results in the loss of sensorimotor and autonomic functions, which is a significant burden to patients. Furthermore, nerve injuries greater than the limiting gap length require surgical repair. Although autografts are the preferred ...

Royal Soc Chemistry2024