Lucie Carrié Tillard

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Three-dimensional organoid culture technologies have revolutionized cancer research by allowing for more realistic and scalable reproductions of both tumour and microenvironmental structures 1-3 . This has enabled better modelling of low-complexity cancer ...

Although the advent of organoids has opened unprecedented perspectives for basic and translational research, immune system-related organoids remain largely underdeveloped. Here, we established organoids from the thymus, the lymphoid organ responsible for T ...

Existing organoid models fall short of fully capturing the complexity of cancer because they lack sufficient multicellular diversity, tissue-level organization, biological durability and experimental flexibility. Thus, many multifactorial cancer processes, ...

Immunotherapy has emerged as a new standard of care for certain cancer patients with specific cellular and molecular makeups. However, there is still an unmet need for ex vivo models able to readily assess the effectiveness of immunotherapeutic treatments ...

Lucie Carrié Tillard

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Spatiotemporally resolved colorectal oncogenesis in mini-colons ex vivo

Thymic epithelial organoids mediate T-cell development

Patient-derived mini-colons enable long-term modeling of tumor–microenvironment complexity

Probing the killing potency of tumor-infiltrating lymphocytes on microarrayed colorectal cancer tumoroids