Publications by Shiyu Cheng | EPFL Graph Search

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The billion tons of synthetic-polymer-based materials (i.e. plastics) produced yearly are a great challenge for humanity. Nature produces even more natural polymers, yet they are sustainable. Proteins are sequence-defined natural polymers that are constant ...

Cells cope with and adapt to ever-changing environmental conditions. Sophisticated regulatory networks allow cells to adjust to these fluctuating environments. One such archetypal system is the Saccharomyces cerevisiae Pho regulon. When external inorganic ...

Advances in bioelectronics have great potential to address unsolved biomedical problems in the cardiovascular system. By using poly (L-lactide-co-epsilon-caprolactone), which encapsulates liquid metal to make flexible and biodegradable electrical circuitry ...

Gene regulatory networks (GRNs) play a crucial role in an organism's response to changing environmental conditions. Cellular behaviors typically result from the integration of multiple gene outputs, and their regulation often demands precise control of num ...

Binding to binding site clusters has yet to be characterized in depth, and the functional relevance of low-affinity clusters remains uncertain. We characterized transcription factor binding to low-affinity clusters in vitro and found that transcription fac ...

Shiyu Cheng

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Nature-Inspired Circular-Economy Recycling for Proteins: Proof of Concept

Perfect adaptation achieved by transport limitations governs the inorganic phosphate response in S. cerevisiae

Electronic Blood Vessel

Quantitative characterization of the inorganic phosphate gene regulatory networks in S. cerevisiae and bottom up engineering an orthogonal gene network

Systematic analysis of low-affinity transcription factor binding site clusters in vitro and in vivo establishes their functional relevance