Publications by Thomas Yu | EPFL Graph Search

Related publications (23)

Revisiting the T-2 spectrum imaging inverse problem: Bayesian regularized non-negative least squares

Jean-Philippe Thiran, Tobias Kober, Tom Hilbert, Erick Jorge Canales Rodriguez, Marco Pizzolato, Thomas Yu

Multi-echo T-2 magnetic resonance images contain information about the distribution of T-2 relaxation times of compartmentalized water, from which we can estimate relevant brain tissue properties such as the myelin water fraction (MWF). Regularized non-neg ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2021

Variability and reproducibility of multi-echo T2 relaxometry: Insights from multi-site, multi-session and multi-subject MRI acquisitions

Jean-Philippe Thiran, Tobias Kober, Elda Fischi Gomez, Alessandro Daducci, Tom Hilbert, Elena Beanato, Gabriel Girard, Julia Brügger, Gian Franco Piredda, Friedhelm Christoph Hummel, Takuya Morishita, Maximilian Jonas Wessel, Philipp Johannes Koch, Erick Jorge Canales Rodriguez, Marco Pizzolato, Andéol Geoffroy Cadic-Melchior, Thomas Yu, Chang-Hyun Park

Quantitative magnetic resonance imaging (qMRI) can increase the specificity and sensitivity of conventional weighted MRI to underlying pathology by comparing meaningful physical or chemical parameters, measured in physical units, with normative values acqu ...

2022

Individually optimized dynamic parallel transmit pulses for 3D high‐resolution SPACE imaging at 7T

Bénédicte Marie Maréchal, Tom Hilbert, Emilie Claire Sleight, Jocelyn Philippe, Thomas Yu, Tommaso Di Noto, Lina Bacha, Natalia Pato Montemayor

Purpose: Although clinical 7T MRI offers various advantages compared to lower field strengths, achieving spatially uniform flip angle distributions remains a challenge. Sampling Perfection with Application optimized Contrast using different flip angle Evol ...

Wiley2025

Combining Model Driven and Data Driven Approaches for Inverse Problems in Parameter Estimation and Image Reconstruction: From Modelling to Validation

Thomas Yu

Machine learning has become the state of the art for the solution of the diverse inverse problems arising from computer vision and medical imaging, e.g. denoising, super-resolution, de-blurring, reconstruction from scanner data, quantitative magnetic reson ...

EPFL2022

The 2024 Magnonics Roadmap

Dirk Grundler, Ping Che, Thomas Yu, Qi Wang

Magnonics is a research field that has gained an increasing interest in both the fundamental and applied sciences in recent years. This field aims to explore and functionalize collective spin excitations in magnetically ordered materials for modern informa ...

2024

Model-informed machine learning for multi-component T2 relaxometry

Jean-Philippe Thiran, Meritxell Bach Cuadra, Tobias Kober, Elda Fischi Gomez, Cristina Granziera, Tom Hilbert, Muhamed Barakovic, Gian Franco Piredda, Erick Jorge Canales Rodriguez, Marco Pizzolato, Thomas Yu

Recovering the distribution from multi-echo magnetic resonance (MR) signals is challenging but has high potential as it provides biomarkers characterizing the tissue micro-structure, such as the myelin water fraction (MWF). In this work, we propose to comb ...

2020

Gray-matter-specific MR imaging improves the detection of epileptogenic zones in focal cortical dysplasia: A new sequence called fluid and white matter suppression (FLAWS)

Tobias Kober, Thomas Yu, Xin Chen

Objectives: To evaluate the diagnostic value and characteristic features of FCD epileptogenic zones using a novel sequence called fluid and white matter suppression (FLAWS). ...

ELSEVIER SCI LTD2018

In-Silico Trained AI for Enhanced T2Spectrum Imaging and Myelin Water Fraction Mapping in Preclinical 7T MRI

Jean-Philippe Thiran, Erick Jorge Canales Rodriguez, Thomas Yu

This study introduces a Machine Learning (ML) approach for estimating the T2 spectrum and myelin water fraction (MWF) using multi-echo T2 (MET2) data from preclinical 7T Magnetic Resonance Imaging (MRI) scanners. ML methods have shown promise in MWF estima ...

IEEE Computer Society2024

DWI Simulation-Assisted Machine Learning Models for Microstructure Estimation

Jean-Philippe Thiran, Muhamed Barakovic, Gabriel Girard, Jonathan Rafael Patino Lopez, Erick Jorge Canales Rodriguez, Marco Pizzolato, Thomas Yu

Diffusion MRI (DW-MRI) allows for the detailed exploration of the brain white matter microstructure, with applications in both research and the clinic. However, state-of-the-art methods for microstructure estimation suffer from known limitations, such as t ...

Springer Nature2020

Robust Biophysical Parameter Estimation with a Neural Network Enhanced Hamiltonian Markov Chain Monte Carlo Sampler

Jean-Philippe Thiran, Gabriel Girard, Jonathan Rafael Patino Lopez, Erick Jorge Canales Rodriguez, Marco Pizzolato, Thomas Yu

Probabilistic parameter estimation in model fitting runs the gamut from maximum likelihood or maximum a posteriori point estimates from optimization to Markov Chain Monte Carlo (MCMC) sampling. The latter, while more computationally intensive, generally pr ...

SPRINGER INTERNATIONAL PUBLISHING AG2019

Tractography dissection variability: What happens when 42 groups dissect 14 white matter bundles on the same dataset?

Jonathan Rafael Patino Lopez, Thomas Yu

White matter bundle segmentation using diffusion MRI fiber tractography has become the method of choice to identify white matter fiber pathways in vivo in human brains. However, like other analyses of complex data, there is considerable variability in segm ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2021

A Fetal Brain magnetic resonance Acquisition Numerical phantom (FaBiAN)

Tobias Kober, Tom Hilbert, Thomas Yu

Accurate characterization of in utero human brain maturation is critical as it involves complex and interconnected structural and functional processes that may influence health later in life. Magnetic resonance imaging is a powerful tool to investigate equ ...

Nature Portfolio2022

Comparison of non-parametric T2 relaxometry methods for myelin water quantification

Jean-Philippe Thiran, Nicolas Kunz, Tobias Kober, Alessandro Daducci, Tom Hilbert, Gian Franco Piredda, Erick Jorge Canales Rodriguez, Marco Pizzolato, Thomas Yu

Multi-component T2 relaxometry allows probing tissue microstructure by assessing compartment-specific T2 relaxation times and water fractions, including the myelin water fraction. Non-negative least squares (NNLS) with zero-order Tikhonov regularization is ...

2021

Slice Estimation in Diffusion MRI of Neonatal and Fetal Brains in Image and Spherical Harmonics Domains Using Autoencoders

Meritxell Bach Cuadra, Gabriel Girard, Erick Jorge Canales Rodriguez, Thomas Yu

Diffusion MRI (dMRI) of the developing brain can provide valuable insights into the white matter development. However, slice thickness in fetal dMRI is typically high (i.e., 3-5 mm) to freeze the in-plane motion, which reduces the sensitivity of the dMRI s ...

SPRINGER INTERNATIONAL PUBLISHING AG2022

The 2021 Magnonics Roadmap

Dirk Grundler, Joyeeta Sinha, Heena Yang, Thomas Yu

Magnonics is a budding research field in nanomagnetism and nanoscience that addresses the use of spin waves (magnons) to transmit, store, and process information. The rapid advancements of this field during last one decade in terms of upsurge in research p ...

2021

Benefiting From Bicubically Down-Sampled Images for Learning Real-World Image Super-Resolution

Jean-Philippe Thiran, Mohammad Saeed Rad, Claudiu-Cristian Musat, Hazim Kemal Ekenel, Seyedbehzad Bozorgtabar, Thomas Yu

Super-resolution (SR) has traditionally been based on pairs of high-resolution images (HR) and their low-resolution (LR) counterparts obtained artificially with bicubic downsampling. However, in real-world SR, there is a large variety of realistic image de ...

2021

Test-Time Adaptation for Super-Resolution: You Only Need to Overfit on a Few More Images

Jean-Philippe Thiran, Mohammad Saeed Rad, Seyedbehzad Bozorgtabar, Thomas Yu

Existing reference (RF)-based super-resolution (SR) models try to improve perceptual quality in SR under the assumption of the availability of high-resolution RF images paired with low-resolution (LR) inputs at testing. As the RF images should be similar i ...

IEEE COMPUTER SOC2021

Simulated Half-Fourier Acquisitions Single-shot Turbo Spin Echo (HASTE) of the Fetal Brain: Application to Super-Resolution Reconstruction

Meritxell Bach Cuadra, Patric Hagmann, Reto Meuli, Tobias Kober, Tom Hilbert, Thomas Yu

Accurate characterization of in utero human brain maturation is critical as it involves complex interconnected structural and functional processes that may influence health later in life. Magnetic resonance imaging is a powerful tool complementary to the u ...

SPRINGER INTERNATIONAL PUBLISHING AG2021

Insights from the IronTract challenge: Optimal methods for mapping brain pathways from multi-shell diffusion MRI

Jean-Philippe Thiran, Elda Fischi Gomez, Gabriel Girard, Gaëtan Olivier D Rensonnet, Jonathan Rafael Patino Lopez, Erick Jorge Canales Rodriguez, Marco Pizzolato, Thomas Yu

Limitations in the accuracy of brain pathways reconstructed by diffusion MRI (dMRI) tractography have received considerable attention. While the technical advances spearheaded by the Human Connectome Project (HCP) led to significant improvements in dMRI da ...

ACADEMIC PRESS INC ELSEVIER SCIENCE2022

MPRAGE to MP2RAGE UNI translation via generative adversarial network improves the automatic tissue and lesion segmentation in multiple sclerosis patients

Jean-Philippe Thiran, Meritxell Bach Cuadra, Cristina Granziera, Thomas Yu, Francesco La Rosa

Background and objective: Compared to the conventional magnetization-prepared rapid gradient-echo imaging (MPRAGE) MRI sequence, the specialized magnetization prepared 2 rapid acquisition gradient echoes (MP2RAGE) shows a higher brain tissue and lesion con ...

2021