Publications by Ali Ghasemi | EPFL Graph Search

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Dendritic cells (DCs) are specialized myeloid cells with the ability to uptake, process, and present antigens to T lymphocytes. They also generate cytokine and chemokine gradients that regulate immune cell trafficking, activation, and function. Monocyte-de ...

Dendritic cells (DCs) are antigen-presenting myeloid cells that regulate T cell activation, trafficking and function. Monocyte-derived DCs pulsed with tumor antigens have been tested extensively for therapeutic vaccination in cancer, with mixed clinical re ...

Blood cells called myeloid cells can facilitate metastasis - the spread of a tumour to distant organs. Taming these cells with drugs that alter the chemical structure of their DNA limits metastasis in mice. ...

Disclosed herein are engineered progenitor cells and methods of using the same. Also disclosed herein are engineered cells differentiated from engineered progenitor cells of the present disclosure. Also disclosed herein are methods of treating a condition ...

Ali Ghasemi

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Cytokine-armed dendritic cell progenitors for antigen-agnostic cancer immunotherapy

Cytokine-armed dendritic cell progenitors for antigen-agnostic cancer immunotherapy

Tweaking DNA of myeloid cells curbs cancer spread

Engineered progenitor cells and methods of use