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Yahya Mohammadzadeh

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Related publications (4)

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Cytokine-armed dendritic cell progenitors for antigen-agnostic cancer immunotherapy

Luqing Li, Michele De Palma, Nahal Mansouri, Ali Ghasemi, Alan Nicolas Thierry Guichard, Yahya Mohammadzadeh, Bruno Torchia

Dendritic cells (DCs) are antigen-presenting myeloid cells that regulate T cell activation, trafficking and function. Monocyte-derived DCs pulsed with tumor antigens have been tested extensively for therapeutic vaccination in cancer, with mixed clinical re ...

Nature Portfolio2023

Engineering a synthetic signaling network in dendritic cells to improve anti-tumoral immunity

Yahya Mohammadzadeh

Effective induction of anti-tumor immunity requires dendritic cells (DCs) to internalize, process and present tumor antigens to T cells. However, the hostile tumor microenvironment (TME) impedes this process by suppressing DC maturation and antigen present ...

EPFL2024

Game changers in science and technology- now and beyond

Yahya Mohammadzadeh

The recent devastating pandemic has drastically reminded humanity of the importance of constant scientific and technological progress. A strong interdisciplinary dialogue between academic and industrial scientists of various specialties, entrepreneurs, man ...

ELSEVIER SCIENCE INC2023

Boosting dendritic cell nanovaccines

Michele De Palma, Yahya Mohammadzadeh

A preclinical study reports a platform for the generation of dendritic cell-derived nanovesicles with enhanced immunostimulatory function, which demonstrate promising antitumoural activity in mouse models and might overcome some of the shortcomings of earl ...

Nature Portfolio2022