Sundar Ram Naganathan

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The mesothelium lines body cavities and surrounds internal organs, widely contributing to homeostasis and regeneration. Mesothelium disruptions cause visceral anomalies and mesothelioma tumors. Nonetheless, the embryonic emergence of mesothelia remains inc ...

Rhythmic and sequential segmentation of the growing vertebrate body relies on the segmentation clock, a multi-cellular oscillating genetic network. The clock is visible as tissue-level kinematic waves of gene expression that travel through the presomitic m ...

One of the great challenges in biology is to understand the mechanisms by which morphogenetic processes arise from molecular activities. We investigated this problem in the context of actomyosin-based cortical flow in C. elegans zygotes, where large-scale ...

The body axis of vertebrate embryos is periodically segmented into bilaterally symmetric pairs of somites(1,2). The anteroposterior length of somites, their position and left-right symmetry are thought to be molecularly determined before somite morphogenes ...

The body axis of vertebrates is subdivided into repetitive compartments called somites, which give rise primarily to the segmented architecture of the musculoskeletal system in the adult body. Somites form in a sequential and rhythmic manner in embryos and ...

Sundar Ram Naganathan

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Hand2 delineates mesothelium progenitors and is reactivated in mesothelioma

Cell-autonomous timing drives the vertebrate segmentation clock's wave pattern

Morphogenetic degeneracies in the actomyosin cortex

Left-right symmetry of zebrafish embryos requires somite surface tension

Patterning and mechanics of somite boundaries in zebrafish embryos