Publications by Suiyang Liao | EPFL Graph Search

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Accurate nanoparticle size determination is essential across various research domains, with many functionalities in nanoscience and biomedical research being size-dependent. Although electron microscopy is capable of resolving a single particle down to the ...

Single-chain nanoparticles (SCNPs) are a type of polymeric nanoparticles formed by collapsing/folding individual polymer chains via intra-molecular interactions. Their emergence holds promise to construct sub-20 nm polymeric nanoparticles with defined stru ...

Protein therapeutics have enormous potential for transforming the treatment of intracellular cell disorders, such as genetic disorders and cancers. Due to proteins’ cell-membrane impermeability, protein-based drugs against intracellular targets require eff ...

In this work we show that it is possible to use MALDI-TOF as a tool to quantify the atomic composition and to describe the phase segragation of the surface of ligand-coated, bimetallic AuAg nanoparticles. Our investigation shows that AuAg nanoparticles of ...

Polymers when self-cross-linked into single-chain nanoparticles bear some resemblance to folded proteins; yet proteins have clear energy landscapes that determine precisely folded structures, while single-chain polymer nanoparticles (SCNPs) have more undef ...

Protein drugs have great potential as targeted therapies, yet their application suffers from several drawbacks, such as instability, short half-life, and adverse immune responses. Thus, protein delivery approaches based on stimuli-responsive nanocarriers c ...

Most nanoparticles' parameters affect their interactions with cells. To date, all the parameters studied are basically static (e.g., size, shape, ligands, and charge). This is unfortunate, because proteins have struc-tural dynamics that most nanoparticles ...

Suiyang Liao

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Comparative characterisation of non-monodisperse gold nanoparticle populations by X-ray scattering and electron microscopy

Single-Chain Nanoparticles for Intracellular Drug Delivery

Efficient Direct Cytosolic Protein Delivery via Protein-Linker Co-engineering

Quantification of surface composition and segregation on AuAg bimetallic nanoparticles by MALDI MS

Control and Characterization of the Compactness of Single-Chain Nanoparticles

Polymeric Micelles Loading Proteins through Concurrent Ion Complexation and pH-Cleavable Covalent Bonding for In Vivo Delivery

Influence of structural dynamics on cell uptake investigated with single-chain polymeric nanoparticles